Moriah Sandy
Overview
Explore the profile of Moriah Sandy including associated specialties, affiliations and a list of published articles.
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Articles
19
Citations
636
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0
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Recent Articles
1.
Kyaw T, Zhang C, Sandy M, Trepka K, Zhang S, Ramirez Hernandez L, et al.
iScience
. 2024 Jul;
27(6):110122.
PMID: 38947502
Drug efflux transporters are a major determinant of drug efficacy and toxicity. A canonical example is P-glycoprotein (P-gp), an efflux transporter that controls the intestinal absorption of diverse compounds. Despite...
2.
Spanogiannopoulos P, Kyaw T, Guthrie B, Bradley P, Lee J, Melamed J, et al.
Nat Microbiol
. 2022 Sep;
7(10):1605-1620.
PMID: 36138165
Pharmaceuticals have extensive reciprocal interactions with the microbiome, but whether bacterial drug sensitivity and metabolism is driven by pathways conserved in host cells remains unclear. Here we show that anti-cancer...
3.
Sandy M, Bui T, Segura Aba K, Ruiz N, Paszalek J, Connor E, et al.
Microb Ecol
. 2022 Jun;
86(1):408-418.
PMID: 35713682
Fungal symbionts living inside plant leaves ("endophytes") can vary from beneficial to parasitic, but the mechanisms by which the fungi affect the plant host phenotype remain poorly understood. Chemical interactions...
4.
He Y, Gallman A, Xie C, Shen Q, Ma J, Wolfreys F, et al.
J Exp Med
. 2021 Dec;
219(1).
PMID: 34889940
B cell self-tolerance is maintained through multiple checkpoints, including restraints on intracellular signaling and cell trafficking. P2RY8 is a receptor with established roles in germinal center (GC) B cell migration...
5.
Alexander M, Ang Q, Nayak R, Bustion A, Sandy M, Zhang B, et al.
Cell Host Microbe
. 2021 Nov;
30(1):17-30.e9.
PMID: 34822777
Bacterial activation of T helper 17 (Th17) cells exacerbates mouse models of autoimmunity, but how human-associated bacteria impact Th17-driven disease remains elusive. We show that human gut Actinobacterium Eggerthella lenta...
6.
Gallman A, Wolfreys F, Nguyen D, Sandy M, Xu Y, An J, et al.
Sci Immunol
. 2021 Jun;
6(60).
PMID: 34088745
P2RY8 promotes the confinement and growth regulation of germinal center (GC) B cells, and loss of human P2RY8 is associated with B cell lymphomagenesis. The metabolite -geranylgeranyl-l-glutathione (GGG) is a...
7.
Corwin L, Runyon C, Ghanem E, Sandy M, Clark G, Palmer G, et al.
CBE Life Sci Educ
. 2018 May;
17(2):ar20.
PMID: 29749845
Course-based undergraduate research experiences (CUREs) provide a promising avenue to attract a larger and more diverse group of students into research careers. CUREs are thought to be distinctive in offering...
8.
Reitz Z, Sandy M, Butler A
Metallomics
. 2017 Jun;
9(7):824-839.
PMID: 28594012
Bacteria often produce siderophores to facilitate iron uptake. One of the most studied siderophores is enterobactin, the macrolactone trimer of 2,3-dihydroxybenzoyl-l-serine, produced by E. coli and many other enteric bacteria....
9.
Zane H, Naka H, Rosconi F, Sandy M, Haygood M, Butler A
J Am Chem Soc
. 2014 Apr;
136(15):5615-8.
PMID: 24701966
The genome of Vibrio harveyi BAA-1116 contains a nonribosomal peptide synthetase (NRPS) gene cluster (aebA-F) resembling that for enterobactin, yet enterobactin is not produced. A gene predicted to encode a...
10.
Han A, Sandy M, Fishman B, Trindade-Silva A, Soares C, Distel D, et al.
PLoS One
. 2013 Oct;
8(10):e76151.
PMID: 24146831
Shipworms are marine bivalve mollusks (Family Teredinidae) that use wood for shelter and food. They harbor a group of closely related, yet phylogenetically distinct, bacterial endosymbionts in bacteriocytes located in...