Peter J Turnbaugh
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Explore the profile of Peter J Turnbaugh including associated specialties, affiliations and a list of published articles.
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135
Citations
60894
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Recent Articles
1.
Babdor J, Patel R, Davidson B, Noecker C, Rahim M, Bisanz J, et al.
bioRxiv
. 2024 Dec;
PMID: 39677657
Human immune systems are highly variable, with most variation attributable to non-genetic sources. The gut microbiome crucially shapes the immune system; however, its relationship with the baseline immune states of...
2.
Rendina M, Turnbaugh P, Bradley P
bioRxiv
. 2024 Nov;
PMID: 39574613
Xenobiotics, including pharmaceutical drugs, can be metabolized by both host and microbiota, in some cases by homologous enzymes. We conducted a systematic search for all human proteins with gut microbial...
3.
Alexander M, Upadhyay V, Rock R, Ramirez L, Trepka K, Puchalska P, et al.
Cell Rep
. 2024 Nov;
43(11):114891.
PMID: 39500329
Diet can protect from autoimmune disease; however, whether diet acts via the host and/or microbiome remains unclear. Here, we use a ketogenic diet (KD) as a model to dissect these...
4.
Hillege L, Trepka K, Ziemons J, Aarnoutse R, Guthrie B, de Vos-Geelen J, et al.
medRxiv
. 2024 Nov;
PMID: 39484258
Purpose: Unpredictable chemotherapy side effects are a major barrier to successful treatment. Cell culture and mouse experiments indicate that the gut microbiota is influenced by and influences anti-cancer drugs. However,...
5.
Bae M, Le C, Mehta R, Dong X, Pieper L, Ramirez L, et al.
Cell Host Microbe
. 2024 Oct;
32(11):1887-1896.e8.
PMID: 39471822
Gut microbial catechol dehydroxylases are a largely uncharacterized family of metalloenzymes that potentially impact human health by metabolizing dietary polyphenols. Here, we use metatranscriptomics (MTX) to identify highly transcribed catechol-dehydroxylase-encoding...
6.
Stubbs B, Alvarez Azanedo G, Peralta S, Diaz S, Gray W, Alexander L, et al.
PLoS One
. 2024 Sep;
19(9):e0307951.
PMID: 39292659
Background: Frailty is a geriatric syndrome characterized by chronic inflammation and metabolic insufficiency that creates vulnerability to poor outcomes with aging. We hypothesize that interventions which target common underlying mechanism...
7.
Tian Y, Rimal B, Bisanz J, Gui W, Wolfe T, Koo I, et al.
Environ Health Perspect
. 2024 Aug;
132(8):87005.
PMID: 39140734
Background: Exposure to persistent organic pollutants (POPs) and disruptions in the gastrointestinal microbiota have been positively correlated with a predisposition to factors such as obesity, metabolic syndrome, and type 2...
8.
Trepka K, Olson C, Upadhyay V, Zhang C, Turnbaugh P
Annu Rev Pharmacol Toxicol
. 2024 Aug;
65(1):355-373.
PMID: 39107044
Drugs represent our first, and sometimes last, line of defense for many diseases, yet despite decades of research we still do not fully understand why a given drug works in...
9.
Carmody R, Varady K, Turnbaugh P
Cell
. 2024 Jul;
187(15):3857-3876.
PMID: 39059362
The past 50 years of interdisciplinary research in humans and model organisms has delivered unprecedented insights into the mechanisms through which diet affects energy balance. However, translating these results to...
10.
Cyphert E, Liu C, Morales A, Nixon J, Blackford E, Garcia M, et al.
JBMR Plus
. 2024 Jul;
8(8):ziae082.
PMID: 39011468
In a recent study examining the effects of manipulating the gut microbiome on bone, a control group of mice in which the microbiome was altered using a non-caloric, aspartame-based sweetener...