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Morag Robertson

Explore the profile of Morag Robertson including associated specialties, affiliations and a list of published articles. Areas
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Articles 16
Citations 2130
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Recent Articles
1.
Jadeja S, Barnard A, McKie L, Cross S, White J, Robertson M, et al.
Invest Ophthalmol Vis Sci . 2015 Mar; 56(5):3015-26. PMID: 25736793
Purpose: As part of a large scale systematic screen to determine the effects of gene knockout mutations in mice, a retinal phenotype was found in mice lacking the Slc9a8 gene,...
2.
Cross S, Macalinao D, McKie L, Rose L, Kearney A, Rainger J, et al.
PLoS Genet . 2014 May; 10(5):e1004359. PMID: 24809698
Mutations in the LIM-homeodomain transcription factor LMX1B cause nail-patella syndrome, an autosomal dominant pleiotrophic human disorder in which nail, patella and elbow dysplasia is associated with other skeletal abnormalities and...
3.
Navarro P, Festuccia N, Colby D, Gagliardi A, Mullin N, Zhang W, et al.
EMBO J . 2012 Nov; 31(24):4547-62. PMID: 23178592
NANOG, OCT4 and SOX2 form the core network of transcription factors supporting embryonic stem (ES) cell self-renewal. While OCT4 and SOX2 expression is relatively uniform, ES cells fluctuate between states...
4.
Medina B, Paraskevopoulos K, Boehringer J, Sznajder A, Robertson M, Endicott J, et al.
J Biol Chem . 2012 Oct; 287(50):42344-51. PMID: 23038266
The ubiquitin-proteasome system is essential for maintaining a functional cell. Not only does it remove incorrectly folded proteins, it also regulates protein levels to ensure their appropriate spatial and temporal...
5.
Lucas-Herald A, Grosset K, Robertson M, Ahmed S
Br J Gen Pract . 2012 Aug; 62(601):407. PMID: 22867661
No abstract available.
6.
Rainger J, Bengani H, Campbell L, Anderson E, Sokhi K, Lam W, et al.
Hum Mol Genet . 2012 Jun; 21(18):3969-83. PMID: 22692683
Biallelic mutations in the gene encoding DHOdehase [dihydroorotate dehydrogenase (DHODH)], an enzyme required for de novo pyrimidine biosynthesis, have been identified as the cause of Miller (Genée-Weidemann or postaxial acrofacial...
7.
Girdwood D, Robertson M, Gordon C
FEBS Lett . 2012 Jun; 586(10):1522-8. PMID: 22673520
In fission yeast, the only known essential function of Ned8p is the modification of the cullin, Pcu1p, and subsequent Cullin-RING-Ligase (CRL) activation and substrate ubiquitination. We show here that a...
8.
Chambers I, Silva J, Colby D, Nichols J, Nijmeijer B, Robertson M, et al.
Nature . 2007 Dec; 450(7173):1230-4. PMID: 18097409
Nanog is a divergent homeodomain protein found in mammalian pluripotent cells and developing germ cells. Deletion of Nanog causes early embryonic lethality, whereas constitutive expression enables autonomous self-renewal of embryonic...
9.
Robertson M, Stenhouse F, Colby D, Marland J, Nichols J, Tweedie S, et al.
Mamm Genome . 2006 Jul; 17(7):732-43. PMID: 16845474
The Nanog gene plays a key role in the pluripotency of early embryonic cells in vitro and in vivo. In this article retrotransposed copies of Nanog, termed NanogPc and NanogPd,...
10.
Robertson M
Drug Discov Today . 2004 Sep; 9(16):684-5. PMID: 15341776
No abstract available.