Peter M Siegel
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Explore the profile of Peter M Siegel including associated specialties, affiliations and a list of published articles.
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108
Citations
7978
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Recent Articles
1.
Najafian K, Rehany B, Nowakowski A, Ghazimoghadam S, Pierre K, Zakarian R, et al.
Neurooncol Adv
. 2024 Dec;
6(1):vdae200.
PMID: 39679176
Background: Brain metastasis invasion pattern (BMIP) is an emerging biomarker associated with recurrence-free and overall survival in patients, and differential response to therapy in preclinical models. Currently, BMIP can only...
2.
Minarrieta L, Annis M, Audet-Delage Y, Kuasne H, Pacis A, St-Louis C, et al.
Sci Adv
. 2024 Nov;
10(45):eadm8212.
PMID: 39504368
Mitochondrial dynamics orchestrate many essential cellular functions, including metabolism, which is instrumental in promoting cancer growth and metastatic progression. However, how mitochondrial dynamics influences metastatic progression remains poorly understood. Here,...
3.
Heath J, Mirabelli C, Annis M, Sabourin V, Hebert S, Findlay S, et al.
Cancer Res
. 2024 Aug;
84(22):3743-3760.
PMID: 39137399
The pogo transposable element-derived zinc finger protein, POGZ, is notably associated with neurodevelopmental disorders through its role in gene transcription. Many proteins involved in neurological development are often dysregulated in...
4.
Biondini M, Lehuede C, Tabaries S, Annis M, Pacis A, Ma E, et al.
Redox Biol
. 2024 Jul;
75:103276.
PMID: 39053265
Metabolic rewiring is essential for tumor growth and progression to metastatic disease, yet little is known regarding how cancer cells modify their acquired metabolic programs in response to different metastatic...
5.
Tabaries S, Robert A, Marcil A, Ling B, Acchione M, Lippens J, et al.
Mol Cancer Ther
. 2024 Jun;
23(10):1459-1470.
PMID: 38902871
We have previously demonstrated that Claudin-2 is required for colorectal cancer (CRC) liver metastasis. The expression of Claudin-2 in primary CRC is associated with poor survival and highly expressed in...
6.
Cao X, Fang T, Chen M, Ning T, Li J, Siegel P, et al.
Biomaterials
. 2024 Apr;
309:122582.
PMID: 38678699
Cold atmospheric plasma (CAP) is a unique form of physical plasma that has shown great potential for cancer therapy. CAP uses ionized gas to induce lethal oxidative stress on cancer...
7.
Vonniessen B, Tabaries S, Siegel P
Front Oncol
. 2024 Feb;
14:1320766.
PMID: 38371623
Tight junctions (TJs) are large intercellular adhesion complexes that maintain cell polarity in normal epithelia and endothelia. Claudins are critical components of TJs, forming homo- and heteromeric interaction between adjacent...
8.
Dankner M, Maritan S, Priego N, Kruck G, Nkili-Meyong A, Nadaf J, et al.
Neuro Oncol
. 2024 Jan;
26(6):1052-1066.
PMID: 38271182
Background: Compared to minimally invasive brain metastases (MI BrM), highly invasive (HI) lesions form abundant contacts with cells in the peritumoral brain parenchyma and are associated with poor prognosis. Reactive...
9.
Cencic R, Im Y, Naineni S, Moustafa-Kamal M, Jovanovic P, Sabourin V, et al.
Proc Natl Acad Sci U S A
. 2024 Jan;
121(4):e2318093121.
PMID: 38232291
In this study, we aimed to address the current limitations of therapies for macro-metastatic triple-negative breast cancer (TNBC) and provide a therapeutic lead that overcomes the high degree of heterogeneity...
10.
Lewis K, La Selva R, Maldonado E, Annis M, Najyb O, Cepeda Canedo E, et al.
Redox Biol
. 2024 Jan;
70:103028.
PMID: 38211442
Significant efforts have focused on identifying targetable genetic drivers that support the growth of solid tumors and/or increase metastatic ability. During tumor development and progression to metastatic disease, physiological and...