Montserrat Garcia-Closas
Overview
Explore the profile of Montserrat Garcia-Closas including associated specialties, affiliations and a list of published articles.
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451
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23429
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Recent Articles
1.
Mulder C, Yang X, Jee Y, Scott C, Gao C, Cao Y, et al.
Res Sq
. 2025 Jan;
PMID: 39764121
Introduction: Incorporation of mammographic density to breast cancer risk models could improve risk stratification to tailor screening and prevention strategies according to risk. Robust evaluation of the value of adding...
2.
Jia G, Chen Z, Ping J, Cai Q, Tao R, Li C, et al.
Nat Genet
. 2025 Jan;
57(1):80-87.
PMID: 39753771
Genome-wide association studies have identified approximately 200 genetic risk loci for breast cancer, but the causal variants and target genes are mostly unknown. We sought to fine-map all known breast...
3.
Kresovich J, Guranich C, Houghton S, Qian J, Jones M, Boutot M, et al.
Breast Cancer Res
. 2024 Nov;
26(1):169.
PMID: 39593118
Background: Prolactin, a hormone produced by the pituitary gland, regulates breast development and may contribute to breast cancer etiology. However, most epidemiologic studies of prolactin and breast cancer have been...
4.
Stylianou C, Wiggins G, Lau V, Dennis J, Shelling A, Wilson M, et al.
Hum Genet
. 2024 Nov;
143(12):1481-1498.
PMID: 39495297
Known risk loci for endometrial cancer explain approximately one third of familial endometrial cancer. However, the association of germline copy number variants (CNVs) with endometrial cancer risk remains relatively unknown....
5.
Zhu B, Tapinos A, Koka H, Yi Lee P, Zhang T, Zhu W, et al.
Am J Hum Genet
. 2024 Nov;
111(12):2773-2788.
PMID: 39492056
Normal tissues adjacent to the tumor (NATs) may harbor early breast carcinogenesis events driven by field cancerization. Although previous studies have characterized copy-number (CN) and transcriptomic alterations, the evolutionary history...
6.
Sherman M, Winham S, Vierkant R, McCauley B, Scott C, Schrup S, et al.
J Natl Cancer Inst
. 2024 Oct;
117(3):456-464.
PMID: 39412492
Background: Most breast biopsies are diagnosed as benign breast disease, with 1.5- to 4-fold increased breast cancer risk. Apart from pathologic diagnoses of atypical hyperplasia, few factors aid in breast...
7.
Garcia-Closas M, Ahearn T, Gaudet M, Hurson A, Balasubramanian J, Pal Choudhury P, et al.
Am J Epidemiol
. 2024 Oct;
193(12):1882.
PMID: 39362752
No abstract available.
8.
Zanti M, OMahony D, Parsons M, Dorling L, Dennis J, Boddicker N, et al.
medRxiv
. 2024 Sep;
PMID: 39281752
Clinical genetic testing identifies variants causal for hereditary cancer, information that is used for risk assessment and clinical management. Unfortunately, some variants identified are of uncertain clinical significance (VUS), complicating...
9.
Hurson A, Ahearn T, Koka H, Jenkins B, Harris A, Roberts S, et al.
medRxiv
. 2024 Aug;
PMID: 39108508
Background: Breast cancer is comprised of distinct molecular subtypes. Studies have reported differences in risk factor associations with breast cancer subtypes, especially by tumor estrogen receptor (ER) status, but their...
10.
Davidson A, Michailidou K, Parsons M, Fortuno C, Bolla M, Wang Q, et al.
Am J Hum Genet
. 2024 Aug;
111(9):2059-2069.
PMID: 39096911
Co-observation of a gene variant with a pathogenic variant in another gene that explains the disease presentation has been designated as evidence against pathogenicity for commonly used variant classification guidelines....