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Monish Jain

Explore the profile of Monish Jain including associated specialties, affiliations and a list of published articles. Areas
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Articles 24
Citations 551
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Recent Articles
1.
Heudi O, Jain M, Winter S
Biomed Chromatogr . 2024 Apr; 38(7):e5871. PMID: 38599686
We report the development and the validation of a sensitive liquid chromatography-mass spectrometry (LC-MS/MS) method for mometasone furoate (MF) analysis in human plasma. Plasma samples were processed through liquid-liquid extraction...
2.
Sekerel B, Nell H, Laki I, Pak T, Contreras E, Kolarz A, et al.
Clin Drug Investig . 2023 Sep; 43(9):719-728. PMID: 37682405
Background: Indacaterol acetate (IND), a long-acting β-agonist in combination with mometasone furoate (MF), an inhaled corticosteroid (ICS), is being explored as a once-daily (od) treatment for asthma in children. This...
3.
Gauvreau G, Hohlfeld J, FitzGerald J, Boulet L, Cockcroft D, Davis B, et al.
Eur Respir J . 2023 Feb; 61(3). PMID: 36822634
Background: Thymic stromal lymphopoietin (TSLP) is a key upstream regulator driving allergic inflammatory responses. We evaluated the efficacy and safety of ecleralimab, a potent inhaled neutralising antibody fragment against human...
4.
Stasi K, Alshare Q, Jain M, Wald M, Li Y
Transl Vis Sci Technol . 2022 Nov; 11(11):15. PMID: 36394843
Purpose: This first-in-human (FIH) study evaluated the safety, tolerability, pharmacokinetics, and effect on corneal sensitivity of topical ocular SAF312 in healthy participants. Methods: This double-masked, randomized study comprised single-ascending dose...
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Buhl R, Nikolaev I, Tillmann H, Vaidya S, Bartels C, Jain M, et al.
Pulm Pharmacol Ther . 2021 Jul; 70:102068. PMID: 34329722
Once-daily (o.d.) fixed-dose combinations of mometasone furoate/indacaterol acetate (MF/IND) and mometasone furoate/indacaterol acetate/glycopyrronium bromide (MF/IND/GLY), both delivered via the Breezhaler® device, are approved for the maintenance treatment of asthma. Across...
7.
Bartels C, Jain M, Yu J, Tillmann H, Vaidya S
Eur J Drug Metab Pharmacokinet . 2021 May; 46(4):487-504. PMID: 34024035
Background And Objective: Clinical evidence suggests no clinically relevant pharmacokinetic interactions between indacaterol (IND), glycopyrronium (GLY) and mometasone furoate (MF). A population pharmacokinetic (popPK) analysis was conducted to identify structural...
8.
Axford J, Sung M, Manchester J, Chin D, Jain M, Shin Y, et al.
J Med Chem . 2021 Apr; 64(8):4744-4761. PMID: 33822618
Spinal muscular atrophy (SMA) is a debilitating neuromuscular disease caused by low levels of functional survival motor neuron protein (SMN) resulting from a deletion or loss of function mutation of...
9.
Wang X, Bartels C, Kulkarni S, Sangana R, Jain M, Zack J, et al.
Drug Res (Stuttg) . 2021 Mar; 71(6):326-334. PMID: 33682912
No abstract available.
10.
Cheung A, Hurley B, Kerrigan R, Shu L, Chin D, Shen Y, et al.
J Med Chem . 2018 Nov; 61(24):11021-11036. PMID: 30407821
Spinal muscular atrophy (SMA), a rare neuromuscular disorder, is the leading genetic cause of death in infants and toddlers. SMA is caused by the deletion or a loss of function...