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Monique J Rogals

Explore the profile of Monique J Rogals including associated specialties, affiliations and a list of published articles. Areas
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Recent Articles
1.
Williams R, Rogals M, Eletsky A, Huang C, Morris L, Moremen K, et al.
J Magn Reson . 2022 Nov; 345:107336. PMID: 36442299
Not all proteins are amenable to uniform isotopic labeling with C and N, something needed for the widely used, and largely deductive, triple resonance assignment process. Among them are proteins...
2.
Rogals M, Eletsky A, Huang C, Morris L, Moremen K, Prestegard J
ACS Chem Biol . 2022 Nov; 17(12):3527-3534. PMID: 36417668
Glycans attached to glycoproteins can contribute to stability, mediate interactions with other proteins, and initiate signal transduction. Glycan conformation, which is critical to these processes, is highly variable and often...
3.
Khaje N, Eletsky A, Biehn S, Mobley C, Rogals M, Kim Y, et al.
Commun Biol . 2022 May; 5(1):452. PMID: 35551273
High resolution hydroxyl radical protein footprinting (HR-HRPF) is a mass spectrometry-based method that measures the solvent exposure of multiple amino acids in a single experiment, offering constraints for experimentally informed...
4.
Rogals M, Yang J, Williams R, Moremen K, Jonathan Amster I, Prestegard J
Glycobiology . 2020 Sep; 31(4):425-435. PMID: 32902634
Preparation of samples for nuclear magnetic resonance (NMR) characterization of larger proteins requires enrichment with less abundant, NMR-active, isotopes such as 13C and 15N. This is routine for proteins that...
5.
Rogals M, Greenwood A, Kwon J, Lu K, Nicholson L
FEBS J . 2016 Oct; 283(24):4528-4548. PMID: 27790836
The peptidyl prolyl isomerase Pin1 has two domains that are considered to be its binding (WW) and catalytic (PPIase) domains, both of which interact with phosphorylated Ser/Thr-Pro motifs. This shared...
6.
De S, Greenwood A, Rogals M, Kovrigin E, Lu K, Nicholson L
Biochemistry . 2012 Oct; 51(43):8583-96. PMID: 23025283
Peptidyl prolyl cis-trans isomerization acts as an effective molecular timer that plays significant roles in biological and pathological processes. Enzymes such as Pin1 catalyze cis-trans isomerization, accelerating the otherwise slow...
7.
Greenwood A, Rogals M, De S, Lu K, Kovrigin E, Nicholson L
J Biomol NMR . 2011 Sep; 51(1-2):21-34. PMID: 21947912
The phosphorylation-specific peptidyl-prolyl isomerase Pin1 catalyzes the isomerization of the peptide bond preceding a proline residue between cis and trans isomers. To best understand the mechanisms of Pin1 regulation, rigorous...