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Monique E Verhaegen

Explore the profile of Monique E Verhaegen including associated specialties, affiliations and a list of published articles. Areas
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Articles 24
Citations 690
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Recent Articles
1.
Sun L, Verhaegen M, McGue J, Olivei A, Dlugosz A, Frankel T, et al.
Lab Invest . 2024 Aug; 104(10):102128. PMID: 39182611
Merkel cell carcinoma (MCC) is an aggressive cutaneous neuroendocrine carcinoma. Checkpoint inhibitor immunotherapy plays an essential role in management of advanced MCC; however, predictors of immunotherapy response remain poorly defined....
2.
Pedersen E, Verhaegen M, Joseph M, Harms K, Harms P
Front Oncol . 2024 Aug; 14:1413793. PMID: 39136002
Merkel cell carcinoma (MCC) is an aggressive cutaneous neuroendocrine carcinoma thought to arise via either viral (Merkel cell polyomavirus) or ultraviolet-associated pathways. Surgery and radiotherapy have historically been mainstays of...
3.
Choi J, Verhaegen M, Yazdani S, Malik R, Harms P, Mangelberger D, et al.
Neoplasia . 2024 Jun; 55:101019. PMID: 38943995
No abstract available.
4.
Choi J, Verhaegen M, Yazdani S, Malik R, Harms P, Mangelberger D, et al.
Neoplasia . 2024 Apr; 51:100995. PMID: 38574506
No abstract available.
5.
Verhaegen M, Harms P, Van Goor J, Arche J, Patrick M, Wilbert D, et al.
J Clin Invest . 2022 Feb; 132(7). PMID: 35143422
Merkel cell carcinoma (MCC) is an aggressive neuroendocrine skin cancer that frequently carries an integrated Merkel cell polyomavirus (MCPyV) genome and expresses viral transforming antigens (TAgs). MCC tumor cells also...
6.
Gravemeyer J, Spassova I, Verhaegen M, Dlugosz A, Hoffmann D, Lange A, et al.
Oncogene . 2021 Oct; 41(1):37-45. PMID: 34667274
Merkel cell carcinoma (MCC) is a neuroendocrine tumor either induced by integration of the Merkel cell polyomavirus into the cell genome or by accumulation of UV-light-associated mutations (VP-MCC and UV-MCC)....
7.
Harms P, Verhaegen M, Hu K, Hrycaj S, Chan M, Liu C, et al.
Mod Pathol . 2021 Oct; 35(4):506-514. PMID: 34593967
Merkel cell carcinoma (MCC) is an aggressive cutaneous neuroendocrine carcinoma without a known dysplastic precursor. In some cases, MCC is associated with SCCIS in the overlying epidermis; however, the MCC...
8.
Harms P, Verhaegen M, Vo J, Tien J, Pratt D, Su F, et al.
J Invest Dermatol . 2021 Sep; 142(3 Pt A):641-652. PMID: 34474081
Merkel cell carcinoma (MCC) is an aggressive cutaneous neuroendocrine carcinoma that is classified as Merkel cell polyomavirus-positive (virus positive [VP]) or Merkel cell polyomavirus-negative (virus negative [VN]). Epigenetic changes, such...
9.
Grachtchouk M, Liu J, Hutchin M, Harms P, Thomas D, Wei L, et al.
Carcinogenesis . 2021 Jun; 42(8):1100-1109. PMID: 34117865
Uncontrolled activation of the Hedgehog (Hh) signaling pathway, operating through GLI transcription factors, plays a central role in the pathogenesis of cutaneous basal cell carcinoma and contributes to the development...
10.
Giblin W, Bringman-Rodenbarger L, Guo A, Kumar S, Monovich A, Mostafa A, et al.
J Clin Invest . 2021 May; 131(12). PMID: 33945506
Cutaneous melanoma remains the most lethal skin cancer, and ranks third among all malignancies in terms of years of life lost. Despite the advent of immune checkpoint and targeted therapies,...