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» Authors » Monika Feigenbutz

Monika Feigenbutz

Explore the profile of Monika Feigenbutz including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 5
Citations 152
Followers 0
Related Specialties
Biochemistry
Molecular Biology
General Medicine
Top 10 Co-Authors
Phil Mitchell
William Garland
Martin Turner
Debora L Makino
Elena Conti
Joe L Costello
Rebecca M Jones
Jonathan A Stead
Benjamin Schuch
Rebecca Jones
Published In
J Biol Chem
EMBO J
RNA
PLoS One
Affiliations
Soon will be listed here.
Recent Articles
1.
The exosome-binding factors Rrp6 and Rrp47 form a composite surface for recruiting the Mtr4 helicase
Schuch B, Feigenbutz M, Makino D, Falk S, Basquin C, Mitchell P, et al.
EMBO J . 2014 Oct; 33(23):2829-46. PMID: 25319414
The exosome is a conserved multi-subunit ribonuclease complex that functions in 3' end processing, turnover and surveillance of nuclear and cytoplasmic RNAs. In the yeast nucleus, the 10-subunit core complex...
2.
The exosome cofactor Rrp47 is critical for the stability and normal expression of its associated exoribonuclease Rrp6 in Saccharomyces cerevisiae
Feigenbutz M, Garland W, Turner M, Mitchell P
PLoS One . 2013 Nov; 8(11):e80752. PMID: 24224060
Rrp6 is a conserved catalytic subunit of the eukaryotic nuclear exosome ribonuclease complex that functions in the productive 3' end maturation of stable RNAs, the degradation of transiently expressed noncoding...
3.
Rrp47 functions in RNA surveillance and stable RNA processing when divorced from the exoribonuclease and exosome-binding domains of Rrp6
Garland W, Feigenbutz M, Turner M, Mitchell P
RNA . 2013 Oct; 19(12):1659-68. PMID: 24106327
The eukaryotic exosome exoribonuclease Rrp6 forms a complex with Rrp47 that functions in nuclear RNA quality control mechanisms, the degradation of cryptic unstable transcripts (CUTs), and in the 3' end...
4.
Assembly of the yeast exoribonuclease Rrp6 with its associated cofactor Rrp47 occurs in the nucleus and is critical for the controlled expression of Rrp47
Feigenbutz M, Jones R, Besong T, Harding S, Mitchell P
J Biol Chem . 2013 Apr; 288(22):15959-70. PMID: 23580640
Rrp6 is a key catalytic subunit of the nuclear RNA exosome that plays a pivotal role in the processing, degradation, and quality control of a wide range of cellular RNAs....
5.
The C-terminal region of the exosome-associated protein Rrp47 is specifically required for box C/D small nucleolar RNA 3'-maturation
Costello J, Stead J, Feigenbutz M, Jones R, Mitchell P
J Biol Chem . 2010 Dec; 286(6):4535-43. PMID: 21135092
Cells lacking the exosome-associated protein Rrp47 show similar defects in stable RNA processing to those observed in the absence of the catalytic subunit Rrp6, but the precise mechanism(s) by which...