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Joe L Costello

Explore the profile of Joe L Costello including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 2
Citations 77
Followers 0
Related Specialty
Biochemistry
Co-Authors
Jonathan A Stead
Phil Mitchell
Rebecca M Jones
Monika Feigenbutz
Michaela J Livingstone
Published In
Nucleic Acids Res
J Biol Chem
Affiliations
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Recent Articles
1.
The C-terminal region of the exosome-associated protein Rrp47 is specifically required for box C/D small nucleolar RNA 3'-maturation
Costello J, Stead J, Feigenbutz M, Jones R, Mitchell P
J Biol Chem . 2010 Dec; 286(6):4535-43. PMID: 21135092
Cells lacking the exosome-associated protein Rrp47 show similar defects in stable RNA processing to those observed in the absence of the catalytic subunit Rrp6, but the precise mechanism(s) by which...
2.
The PMC2NT domain of the catalytic exosome subunit Rrp6p provides the interface for binding with its cofactor Rrp47p, a nucleic acid-binding protein
Stead J, Costello J, Livingstone M, Mitchell P
Nucleic Acids Res . 2007 Aug; 35(16):5556-67. PMID: 17704127
The exosome complex is a key component of the cellular RNA surveillance machinery and is required for normal 3' end processing of many stable RNAs. Exosome activity requires additional factors...