Monika Bokori-Brown
Overview
Explore the profile of Monika Bokori-Brown including associated specialties, affiliations and a list of published articles.
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22
Citations
727
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Recent Articles
1.
Marshall S, McGill B, Morcrette H, Winlove C, Chimerel C, Petrov P, et al.
Toxins (Basel)
. 2022 Nov;
14(11).
PMID: 36356007
epsilon toxin (Etx) is a pore forming toxin that causes enterotoxaemia in ruminants and may be a cause of multiple sclerosis in humans. To date, most in vitro studies of...
2.
Morcrette H, Bokori-Brown M, Ong S, Bennett L, Wren B, Lewis N, et al.
NPJ Vaccines
. 2019 Aug;
4:32.
PMID: 31372245
A variant form of epsilon toxin (Y30A-Y196A) with mutations, which shows reduced binding to Madin-Darby canine kidney (MDCK) cells and reduced toxicity in mice, has been proposed as the next-generation...
3.
Savva C, Clark A, Naylor C, Popoff M, Moss D, Basak A, et al.
Nat Commun
. 2019 Jun;
10(1):2641.
PMID: 31201325
Epsilon toxin (Etx), a potent pore forming toxin (PFT) produced by Clostridium perfringens, is responsible for the pathogenesis of enterotoxaemia of ruminants and has been suggested to play a role...
4.
Adler D, Linden J, Shetty S, Ma Y, Bokori-Brown M, Titball R, et al.
iScience
. 2019 Apr;
15:39-54.
PMID: 31030181
Clostridium perfringens epsilon toxin (ETX) is hypothesized to mediate blood-brain barrier (BBB) permeability by binding to the myelin and lymphocyte protein (MAL) on the luminal surface of endothelial cells (ECs)....
5.
Bokori-Brown M, Metz J, Petrov P, Mussai F, De Santo C, Smart N, et al.
Front Oncol
. 2018 Dec;
8:553.
PMID: 30538953
Acute Lymphoblastic Leukemia (ALL) remains the most frequent cause of cancer-related mortality in children and novel therapies are needed for the treatment of relapsed/refractory childhood ALL. One approach is the...
6.
Wagley S, Bokori-Brown M, Morcrette H, Malaspina A, DArcy C, Gnanapavan S, et al.
Mult Scler
. 2018 Apr;
25(5):653-660.
PMID: 29681209
Background: It was recently reported that, using Western blotting, some multiple sclerosis (MS) patients in the United States had antibodies against epsilon toxin (Etx) from Clostridium perfringens, suggesting that the...
7.
Bokori-Brown M, Martin T, Naylor C, Basak A, Titball R, Savva C
Nat Commun
. 2016 Apr;
7:11293.
PMID: 27048994
Lysenin from the coelomic fluid of the earthworm Eisenia fetida belongs to the aerolysin family of small β-pore-forming toxins (β-PFTs), some members of which are pathogenic to humans and animals....
8.
Bokori-Brown M, Petrov P, Khafaji M, Mughal M, Naylor C, Shore A, et al.
J Biol Chem
. 2016 Mar;
291(19):10210-27.
PMID: 26984406
This study investigated the effect of the biochemical and biophysical properties of the plasma membrane as well as membrane morphology on the susceptibility of human red blood cells to the...
9.
Fernandes da Costa S, Mot D, Geeraerts S, Bokori-Brown M, Van Immerseel F, Titball R
Avian Pathol
. 2016 Jan;
45(3):381-8.
PMID: 26743457
Necrotic enteritis toxin B (NetB) is a pore-forming toxin produced by Clostridium perfringens and has been shown to play a key role in avian necrotic enteritis, a disease causing significant...
10.
Bokori-Brown M, Hall C, Vance C, Fernandes da Costa S, Savva C, Naylor C, et al.
Vaccine
. 2014 Apr;
32(23):2682-7.
PMID: 24709588
Epsilon toxin (Etx) is a β-pore-forming toxin produced by Clostridium perfringens toxinotypes B and D and plays a key role in the pathogenesis of enterotoxemia, a severe, often fatal disease...