Mona Al-Mugotir
Overview
Explore the profile of Mona Al-Mugotir including associated specialties, affiliations and a list of published articles.
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7
Citations
116
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0
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Recent Articles
1.
Al-Mugotir M, Lovelace J, George J, Bessho M, Pal D, Struble L, et al.
PLoS One
. 2021 Mar;
16(3):e0248941.
PMID: 33784323
Synthetic lethality is a successful strategy employed to develop selective chemotherapeutics against cancer cells. Inactivation of RAD52 is synthetically lethal to homologous recombination (HR) deficient cancer cell lines. Replication protein...
2.
Al-Mugotir M, Kolar C, Vance K, Kelly D, Natarajan A, Borgstahl G
Anal Biochem
. 2019 Feb;
569:46-52.
PMID: 30707898
Due to the therapeutic potential of targeting protein-protein interactions (PPIs) there is a need for easily executed assays to perform high throughput screening (HTS) of inhibitors. We have developed and...
3.
Spagnol G, Al-Mugotir M, Kopanic J, Zach S, Li H, Trease A, et al.
Biopolymers
. 2015 Nov;
105(3):143-62.
PMID: 26542351
The connexin carboxyl-terminal (CxCT) domain plays a role in the trafficking, localization, and turnover of gap junction channels, as well as the level of gap junction intercellular communication via numerous...
4.
Kopanic J, Al-Mugotir M, Zach S, Das S, Grosely R, Sorgen P
Front Pharmacol
. 2013 Aug;
4:106.
PMID: 23986705
A major problem for structural characterization of membrane proteins, such as connexins, by nuclear magnetic resonance (NMR) occurs at the initial step of the process, the production of sufficient amounts...
5.
Grosely R, Kopanic J, Nabors S, Kieken F, Spagnol G, Al-Mugotir M, et al.
J Biol Chem
. 2013 Jul;
288(34):24857-70.
PMID: 23828237
Phosphorylation of the connexin43 C-terminal (Cx43CT) domain regulates gap junction intercellular communication. However, an understanding of the mechanisms by which phosphorylation exerts its effects is lacking. Here, we test the...
6.
Liu X, Togo S, Al-Mugotir M, Kim H, Fang Q, Kobayashi T, et al.
Respir Res
. 2008 Sep;
9:66.
PMID: 18811964
Background: We have previously reported that low concentrations of cigarette smoke extract induce DNA damage without leading to apoptosis or necrosis in human bronchial epithelial cells (HBECs), and that IL-6/STAT3...
7.
Fang Q, Liu X, Al-Mugotir M, Kobayashi T, Abe S, Kohyama T, et al.
Am J Respir Cell Mol Biol
. 2006 Jul;
35(6):714-21.
PMID: 16858010
Degradation of preexisting and newly synthesized extracellular matrix is thought to play an important role in tissue remodeling. The current study evaluated whether thrombin and TNF-alpha/IL-1beta could collaboratively induce collagen...