Momoko Horikoshi
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Explore the profile of Momoko Horikoshi including associated specialties, affiliations and a list of published articles.
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70
Citations
7678
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Recent Articles
1.
Flanagan J, Liu X, Ortega-Reyes D, Tomizuka K, Matoba N, Akiyama M, et al.
Commun Biol
. 2024 Dec;
7(1):1665.
PMID: 39702642
To improve imputation quality for genome-wide association studies (GWAS) conducted on the Japanese population, we developed and evaluated four Japanese population-specific reference panels. These panels were constructed through the augmentation...
2.
Koyama S, Liu X, Koike Y, Hikino K, Koido M, Li W, et al.
Nat Genet
. 2024 Oct;
56(10):2027-2035.
PMID: 39363016
Human genetic variants are associated with many traits through largely unknown mechanisms. Here, combining approximately 260,000 Japanese study participants, a Japanese-specific genotype reference panel and statistical fine-mapping, we identified 4,423...
3.
Kentistou K, Kaisinger L, Stankovic S, Vaudel M, Mendes de Oliveira E, Messina A, et al.
Nat Genet
. 2024 Jul;
56(8):1763-1764.
PMID: 38982295
No abstract available.
4.
Kentistou K, Kaisinger L, Stankovic S, Vaudel M, Mendes de Oliveira E, Messina A, et al.
Nat Genet
. 2024 Jul;
56(7):1397-1411.
PMID: 38951643
Pubertal timing varies considerably and is associated with later health outcomes. We performed multi-ancestry genetic analyses on ~800,000 women, identifying 1,080 signals for age at menarche. Collectively, these explained 11%...
5.
Liu X, Koyama S, Tomizuka K, Takata S, Ishikawa Y, Ito S, et al.
Sci Adv
. 2024 Apr;
10(16):eadi8419.
PMID: 38630824
We generated Japanese Encyclopedia of Whole-Genome/Exome Sequencing Library (JEWEL), a high-depth whole-genome sequencing dataset comprising 3256 individuals from across Japan. Analysis of JEWEL revealed genetic characteristics of the Japanese population...
6.
Suzuki K, Hatzikotoulas K, Southam L, Taylor H, Yin X, Lorenz K, et al.
Nature
. 2024 Feb;
627(8003):347-357.
PMID: 38374256
Type 2 diabetes (T2D) is a heterogeneous disease that develops through diverse pathophysiological processes and molecular mechanisms that are often specific to cell type. Here, to characterize the genetic contribution...
7.
Liu X, Matsunami M, Horikoshi M, Ito S, Ishikawa Y, Suzuki K, et al.
Mol Biol Evol
. 2023 Oct;
40(10).
PMID: 37903429
Natural selection signatures across Japanese subpopulations are under-explored. Here we conducted genome-wide selection scans with 622,926 single nucleotide polymorphisms for 20,366 Japanese individuals, who were recruited from the main-islands of...
8.
Ito S, Liu X, Ishikawa Y, Conti D, Otomo N, Kote-Jarai Z, et al.
Nat Commun
. 2023 Aug;
14(1):4863.
PMID: 37612283
Prostate cancer (PrCa) is the second most common cancer worldwide in males. While strongly warranted, the prediction of mortality risk due to PrCa, especially before its development, is challenging. Here,...
9.
Kentistou K, Kaisinger L, Stankovic S, Vaudel M, de Oliveira E, Messina A, et al.
medRxiv
. 2023 Jul;
PMID: 37503126
Pubertal timing varies considerably and has been associated with a range of health outcomes in later life. To elucidate the underlying biological mechanisms, we performed multi-ancestry genetic analyses in ~800,000...
10.
Suzuki K, Hatzikotoulas K, Southam L, Taylor H, Yin X, Lorenz K, et al.
medRxiv
. 2023 Apr;
PMID: 37034649
Type 2 diabetes (T2D) is a heterogeneous disease that develops through diverse pathophysiological processes. To characterise the genetic contribution to these processes across ancestry groups, we aggregate genome-wide association study...