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Mojgan Masoodi

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Articles 58
Citations 1765
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Recent Articles
1.
Sugimoto A, Saito Y, Wang G, Sun Q, Yin C, Lee K, et al.
Nature . 2025 Mar; PMID: 40074890
Hepatic stellate cells (HSCs) have a central pathogenetic role in the development of liver fibrosis. However, their fibrosis-independent and homeostatic functions remain poorly understood. Here we demonstrate that genetic depletion...
2.
Seubnooch P, Montani M, Dufour J, Masoodi M
J Lipid Res . 2024 Jul; 65(9):100599. PMID: 39032559
Alteration in lipid metabolism plays a pivotal role in developing metabolic dysfunction-associated steatohepatitis (MASH). However, our understanding of alteration in lipid metabolism across liver zonation in MASH remains limited. Within...
3.
Mendoza Y, Tsouka S, Semmler G, Seubnooch P, Freiburghaus K, Mandorfer M, et al.
J Hepatol . 2024 Jun; 81(6):983-994. PMID: 38944391
Background & Aims: Regression of cirrhosis has been observed in patients with viral and non-viral etiologies of liver disease in whom the underlying cause of liver injury was effectively suppressed....
4.
Nagler M, Nilius H, Michielin G, Masoodi M, Largiader C
Pol Arch Intern Med . 2024 Jun; 134(7-8). PMID: 38884596
Laboratory tests play a central role in medicine, as they help to make diagnoses, assess prognosis and risk of disease, and monitor therapies, thus contributing to 70% of all medical...
5.
Tsouka S, Kumar P, Seubnooch P, Freiburghaus K, St-Pierre M, Dufour J, et al.
Commun Med (Lond) . 2024 Mar; 4(1):39. PMID: 38443644
Background: Metabolic dysfunction-associated steatotic liver disease (MASLD) is a prevalent chronic liver disease worldwide, and can rapidly progress to metabolic dysfunction-associated steatohepatitis (MASH). Accurate preclinical models and methodologies are needed...
6.
Seubnooch P, Montani M, Tsouka S, Claude E, Rafiqi U, Perren A, et al.
JHEP Rep . 2023 Jun; 5(6):100725. PMID: 37284141
Background & Aims: Lipid metabolism plays an important role in liver pathophysiology. The liver lobule asymmetrically distributes oxygen and nutrition, resulting in heterogeneous metabolic functions. Periportal and pericentral hepatocytes have...
7.
Tsouka S, Masoodi M
Biomolecules . 2023 Feb; 13(2). PMID: 36830612
Over the past decades, pathway analysis has become one of the most commonly used approaches for the functional interpretation of metabolomics data. Although the approach is widely used, it is...
8.
Bohra S, Achar R, Chidambaram S, Pellegrino C, Laurin J, Masoodi M, et al.
Eur J Neurosci . 2022 Apr; 56(1):3738-3754. PMID: 35478208
Mitochondria are an autonomous organelle that plays a crucial role in the metabolic aspects of a cell. Cortical spreading depression (CSD) and fluctuations in the cerebral blood flow have for...
9.
Jouffe C, Weger B, Martin E, Atger F, Weger M, Gobet C, et al.
Proc Natl Acad Sci U S A . 2022 Mar; 119(10):e2200083119. PMID: 35238641
SignificanceWhile increasing evidence associates the disruption of circadian rhythms with pathologic conditions, including obesity, type 2 diabetes, and nonalcoholic fatty liver diseases (NAFLD), the involved mechanisms are still poorly described....
10.
Masoodi M, Peschka M, Schmiedel S, Haddad M, Frye M, Maas C, et al.
J Mol Med (Berl) . 2022 Jan; 100(4):555-568. PMID: 35064792
The Coronavirus disease 2019 (COVID-19) pandemic is overwhelming the healthcare systems. Identification of systemic reactions underlying COVID-19 will lead to new biomarkers and therapeutic targets for monitoring and early intervention...