Mojgan Djavaheri-Mergny
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Explore the profile of Mojgan Djavaheri-Mergny including associated specialties, affiliations and a list of published articles.
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49
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9022
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Recent Articles
1.
Saei A, Asghari N, Jahangiri B, Cordani M, Nayeri Z, Fard N, et al.
Comput Biol Med
. 2025 Feb;
188:109757.
PMID: 39983356
Cancer treatment is often confounded by development of resistance to chemotherapy. This research explores the complex relationship between p62 (also known as SQSTM1), a multifunctional protein central in cancer signaling...
2.
Alvarez-Valadez K, Sauvat A, Diharce J, Leduc M, Stoll G, Guittat L, et al.
Autophagy
. 2024 Dec;
:1-23.
PMID: 39663580
Cholesterol serves as a vital lipid that regulates numerous physiological processes. Nonetheless, its role in regulating cell death processes remains incompletely understood. In this study, we investigated the role of...
3.
Sanchez-Mendoza S, de Deus-Wagatsuma V, do Nascimento M, Lima K, Machado-Neto J, Djavaheri-Mergny M, et al.
Ann Hematol
. 2024 Dec;
103(12):5405-5416.
PMID: 39661129
Acute myeloid leukemia (AML) with FLT3-ITD mutation represents a quarter of AML patients and is associated with high relapse rate and dismal prognosis. FLT3 tyrosine kinase inhibitors (TKIs) were developed...
4.
Ferret L, Kroemer G, Djavaheri-Mergny M
Cell Stress
. 2024 May;
8:51-55.
PMID: 38800095
In a recent issue in , Sung Min Son unveil a novel layer in the regulation of the mTORC1/autophagy axis by EP300 which can undergo nucleocytoplasmic shuttling in response to...
5.
Anagnostopoulos G, Saavedra E, Lambertucci F, Motino O, Dimitrov J, Roiz-Valle D, et al.
Cell Death Dis
. 2024 Apr;
15(4):249.
PMID: 38582872
Acyl-CoA binding protein (ACBP) encoded by diazepam binding inhibitor (DBI) is an extracellular inhibitor of autophagy acting on the gamma-aminobutyric acid A receptor (GABAR) γ2 subunit (GABARγ2). Here, we show...
6.
Figueiredo J, Djavaheri-Mergny M, Ferret L, Mergny J, Cruz C
Drug Discov Today
. 2024 Feb;
28(12):103808.
PMID: 38414431
Lung cancer (LC) remains a leading cause of mortality worldwide, and new therapeutic strategies are urgently needed. One such approach revolves around the utilization of four-stranded nucleic acid secondary structures,...
7.
Moosavi M, Djavaheri-Mergny M
Cells
. 2023 Feb;
12(3).
PMID: 36766840
Autophagy is a catabolic lysosomal-dependent pathway involved in the degradation of cellular materials, supplying precursor compounds and energy for macromolecule synthesis and metabolic needs [...].
8.
Ferret L, Alvarez-Valadez K, Riviere J, Muller A, Bohalova N, Yu L, et al.
Autophagy
. 2023 Feb;
19(7):1901-1915.
PMID: 36740766
Guanine-quadruplex structures (G4) are unusual nucleic acid conformations formed by guanine-rich DNA and RNA sequences and known to control gene expression mechanisms, from transcription to protein synthesis. So far, a...
9.
Motino O, Lambertucci F, Anagnostopoulos G, Li S, Nah J, Castoldi F, et al.
Proc Natl Acad Sci U S A
. 2022 Oct;
119(41):e2207344119.
PMID: 36191214
Acyl-coenzyme A (CoA)-binding protein (ACBP), also known as diazepam-binding inhibitor (DBI), is an extracellular feedback regulator of autophagy. Here, we report that injection of a monoclonal antibody neutralizing ACBP/DBI (α-DBI)...
10.
Airiau K, Vacher P, Micheau O, Prouzet-Mauleon V, Kroemer G, Moosavi M, et al.
Cells
. 2022 Jan;
11(1).
PMID: 35011619
Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) selectively kills various cancer cell types, but also leads to the activation of signaling pathways that favor resistance to cell death. Here, we investigated...