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Mohsen Sabouri-Ghomi

Explore the profile of Mohsen Sabouri-Ghomi including associated specialties, affiliations and a list of published articles. Areas
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Articles 15
Citations 583
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Recent Articles
1.
Ben Nasr M, Robbins D, Parone P, Usuelli V, Tacke R, Seelam A, et al.
J Immunol . 2022 Mar; 208(7):1554-1565. PMID: 35321879
Type 1 diabetes (T1D) is characterized by the loss of immune self-tolerance, resulting in an aberrant immune responses against self-tissue. A few therapeutics have been partially successful in reverting or...
2.
Ku M, Ke E, Sabouri-Ghomi M, Abadejos J, Freeman B, Nham A, et al.
J Allergy Clin Immunol . 2018 Jun; 142(3):997-1000.e4. PMID: 29857010
No abstract available.
3.
Hodgson L, Spiering D, Sabouri-Ghomi M, Dagliyan O, DerMardirossian C, Danuser G, et al.
Nat Chem Biol . 2016 Aug; 12(10):802-809. PMID: 27501396
Guanine-nucleotide dissociation inhibitors (GDIs) are negative regulators of Rho family GTPases that sequester the GTPases away from the membrane. Here we ask how GDI-Cdc42 interaction regulates localized Cdc42 activation for...
4.
Liu W, Kang S, Huang Z, Wu C, Jin H, Maine C, et al.
J Exp Med . 2016 Aug; 213(9):1901-19. PMID: 27481129
MicroRNA (miRNA) deficiency impairs the generation of T follicular helper (Tfh) cells, but the contribution of individual miRNAs to this phenotype remains poorly understood. In this study, we performed deep...
5.
Ichiyama K, Gonzalez-Martin A, Kim B, Jin H, Jin W, Xu W, et al.
Immunity . 2016 Jun; 44(6):1284-98. PMID: 27332731
T helper 17 (Th17) cells are key players in autoimmune diseases. However, the roles of non-coding RNAs in Th17 cell development and function are largely unknown. We found that deletion...
6.
Ku M, Chang S, Hernandez J, Abadejos J, Sabouri-Ghomi M, Muenchmeier N, et al.
Proc Natl Acad Sci U S A . 2016 Apr; 113(16):E2316-25. PMID: 27044095
To study the development and function of "natural-arising" T regulatory (nTreg) cells, we developed a novel nTreg model on pure nonobese diabetic background using epigenetic reprogramming via somatic cell nuclear...
7.
Jin H, Gonzalez-Martin A, Miletic A, Lai M, Knight S, Sabouri-Ghomi M, et al.
Front Genet . 2015 Dec; 6:340. PMID: 26697058
Transient transfection of chemically synthesized microRNA (miRNA) mimics is being used extensively to study the functions and mechanisms of endogenous miRNAs. However, it remains unclear whether transfected miRNAs behave similarly...
8.
Bethel K, Luttgen M, Damani S, Kolatkar A, Lamy R, Sabouri-Ghomi M, et al.
Phys Biol . 2014 Jan; 11(1):016002. PMID: 24406475
Elevated levels of circulating endothelial cells (CECs) occur in response to various pathological conditions including myocardial infarction (MI). Here, we adapted a fluid phase biopsy technology platform that successfully detects...
9.
Zawistowski J, Sabouri-Ghomi M, Danuser G, Hahn K, Hodgson L
PLoS One . 2013 Nov; 8(11):e79877. PMID: 24224016
RhoA and RhoC GTPases share 92% amino acid sequence identity, yet play different roles in regulating cell motility and morphology. To understand these differences, we developed and validated a biosensor...
10.
Jin H, Oda H, Lai M, Skalsky R, Bethel K, Shepherd J, et al.
EMBO J . 2013 Aug; 32(17):2377-91. PMID: 23921550
MicroRNAs (miRNAs) have been broadly implicated in cancer, but their exact function and mechanism in carcinogenesis remain poorly understood. Elevated miR-17~92 expression is frequently found in human cancers, mainly due...