Mohit Hulsurkar
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Explore the profile of Mohit Hulsurkar including associated specialties, affiliations and a list of published articles.
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10
Citations
352
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Recent Articles
1.
Naderinezhad S, Zhang G, Wang Z, Zheng D, Hulsurkar M, Bakhoum M, et al.
Cancer Lett
. 2023 Aug;
571:216333.
PMID: 37543278
The mechanisms underlying the progression of prostate cancer (PCa) to neuroendocrine prostate cancer (NEPC), an aggressive PCa variant, are largely unclear. Two prominent NEPC phenotypes are elevated NE marker expression...
2.
Wang Z, Hulsurkar M, Zhuo L, Xu J, Yang H, Naderinezhad S, et al.
Neoplasia
. 2021 Oct;
23(11):1147-1165.
PMID: 34706306
Epithelial-mesenchymal transition (EMT) contributes to tumor invasion, metastasis and drug resistance. AKT activation is key in a number of cellular processes. While many positive regulators for either EMT or AKT...
3.
Moreira L, Takawale A, Hulsurkar M, Menassa D, Antanaviciute A, Lahiri S, et al.
Nature
. 2020 Nov;
587(7834):460-465.
PMID: 33149301
Atrial fibrillation, the most common cardiac arrhythmia, is an important contributor to mortality and morbidity, and particularly to the risk of stroke in humans. Atrial-tissue fibrosis is a central pathophysiological...
4.
Campbell H, Quick A, Abu-Taha I, Chiang D, Kramm C, Word T, et al.
Circulation
. 2020 Jul;
142(12):1159-1172.
PMID: 32683896
Background: Enhanced diastolic calcium (Ca) release through ryanodine receptor type-2 (RyR2) has been implicated in atrial fibrillation (AF) promotion. Diastolic sarcoplasmic reticulum Ca leak is caused by increased RyR2 phosphorylation...
5.
Lahiri S, Quick A, Samson-Couterie B, Hulsurkar M, Elzenaar I, van Oort R, et al.
Basic Res Cardiol
. 2020 Jun;
115(4):49.
PMID: 32592107
Heart failure (HF) is a leading cause of morbidity and mortality worldwide. Patients with HF exhibit a loss of junctophilin-2 (JPH2), a structural protein critical in forming junctional membrane complexes...
6.
Alsina K, Hulsurkar M, Brandenburg S, Kownatzki-Danger D, Lenz C, Urlaub H, et al.
Circulation
. 2019 Jun;
140(8):681-693.
PMID: 31185731
Background: Abnormal calcium (Ca) release from the sarcoplasmic reticulum (SR) contributes to the pathogenesis of atrial fibrillation (AF). Increased phosphorylation of 2 proteins essential for normal SR-Ca cycling, the type-2...
7.
Ni L, Scott Jr L, Campbell H, Pan X, Alsina K, Reynolds J, et al.
Circ Res
. 2018 Dec;
124(2):256-262.
PMID: 30582449
Rationale: Somatic overexpression in mice using an adeno-associated virus (AAV) as gene transfer vectors has become a valuable tool to analyze the roles of specific genes in cardiac diseases. The...
8.
Hulsurkar M, Quick A, Wehrens X
J Clin Invest
. 2018 Nov;
128(12):5219-5221.
PMID: 30418170
βIV-Spectrin, along with ankyrin and Ca2+/calmodulin-dependent kinase II (CaMKII), has been shown to form local signaling domains at the intercalated disc, while playing a key role in the regulation of...
9.
Zhang Y, Zheng D, Zhou T, Song H, Hulsurkar M, Su N, et al.
Nat Commun
. 2018 Oct;
9(1):4080.
PMID: 30287808
The incidence of aggressive neuroendocrine prostate cancers (NEPC) related to androgen-deprivation therapy (ADT) is rising. NEPC is still poorly understood, such as its neuroendocrine differentiation (NED) and angiogenic phenotypes. Here...
10.
Sang M, Hulsurkar M, Zhang X, Song H, Zheng D, Zhang Y, et al.
Oncotarget
. 2016 May;
7(29):45171-45185.
PMID: 27191986
Neuroendocrine prostate cancer (NEPC) is an aggressive subtype of prostate cancer that commonly arises through neuroendocrine differentiation (NED) of prostate adenocarcinoma (PAC) after therapy, such as radiation therapy and androgen...