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Mohindar Murugesh Karunakaran

Explore the profile of Mohindar Murugesh Karunakaran including associated specialties, affiliations and a list of published articles. Areas
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Articles 6
Citations 64
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Recent Articles
1.
Herrmann T, Karunakaran M
Eur J Immunol . 2024 Aug; 54(11):e2451068. PMID: 39148158
Vγ9Vδ2 T cells comprise 1-10% of human peripheral blood T cells. As multifunctional T cells with a strong antimicrobial and antitumor potential, they are of strong interest for immunotherapeutic development....
2.
Karunakaran M, Subramanian H, Jin Y, Mohammed F, Kimmel B, Juraske C, et al.
Res Sq . 2023 Feb; PMID: 36824912
Butyrophilin (BTN)-3A and BTN2A1 molecules control TCR-mediated activation of human Vγ9Vδ2 T-cells triggered by phosphoantigens (PAg) from microbes and tumors, but the molecular rules governing antigen sensing are unknown. Here...
3.
Herrmann T, Karunakaran M, Fichtner A
Immunol Rev . 2020 Sep; 298(1):218-236. PMID: 32981055
Both, jawless and jawed vertebrates possess three lymphocyte lineages defined by highly diverse antigen receptors: Two T-cell- and one B-cell-like lineage. In both phylogenetic groups, the theoretically possible number of...
4.
Herrmann T, Fichtner A, Karunakaran M
Cells . 2020 Jun; 9(6). PMID: 32527033
About 1-5% of human blood T cells are Vγ9Vδ2 T cells. Their hallmark is the expression of T cell antigen receptors (TCR) whose γ-chains contain a rearrangement of Vγ9 with...
5.
Fichtner A, Karunakaran M, Starick L, Truman R, Herrmann T
Front Immunol . 2018 Mar; 9:265. PMID: 29527206
1-5% of human blood T cells are Vγ9Vδ2 T cells whose T cell receptor (TCR) contain a rearrangement and a comprising Vδ2-chain. They respond to phosphoantigens (PAgs) like isopentenyl pyrophosphate...
6.
Mattarei A, Enzinger M, Gu S, Karunakaran M, Kimmel B, Berner N, et al.
Chemistry . 2017 Jun; 23(49):11945-11954. PMID: 28631855
Vγ9Vδ2 T cells play an important role in the cross talk of the innate and adaptive immune system. For their activation by phosphoantigens (PAgs), both cell surface receptors, the eponymous...