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Mohd Amir

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Articles 85
Citations 591
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Recent Articles
1.
Amir M, Qureshi M, Musarrat J, Javed S
Biochim Biophys Acta Gen Subj . 2024 Dec; 1869(2):130751. PMID: 39725241
The interaction of drugs with DNA is crucial for understanding their mechanism of action, particularly in the context of gene expression regulation. Erdafitinib (EDB), a pan-FGFR (fibroblast growth factor receptor)...
2.
Tameem M, Amir M, Muslim M, Ahmed R, Khan M, Ahmad M, et al.
Biophys Chem . 2024 Nov; 317:107355. PMID: 39579656
This paper presents the synthesis process of a ligand known as 2-(naphthalene-1-yl)-1H-phenanthro[9,10-d]imidazole (NIP) and its metal complex with zinc (II), denoted as FA-128. The structural validation of FA-128 is accomplished...
3.
Gomaa M, Ahmed A, El Rayes S, Ali I, Fathalla W, Alturki M, et al.
RSC Adv . 2024 Nov; 14(48):35679-35695. PMID: 39524090
We have designed 17 new 2-oxo-3-phenylquinoxalines the chemoselective Michael reaction of 3-phenylquinoxalin-2(1)-one with acrylic acid derivatives. The ester, ethyl 3-(2-oxo-3-phenylquinoxalin-1(2)-yl)propanoate, was reacted with hydroxylamine and hydrazine to produce -hydroxy-3-(2-oxo-3-phenylquinoxalin-1(2)-yl)propanamide and...
4.
Amir M, Shafi S, Parveen S, Reshi A, Ahmad A
Pharmaceuticals (Basel) . 2024 Aug; 17(8). PMID: 39204195
Down Syndrome (DS), characterized by trisomy of chromosome 21, leads to the overexpression of several genes contributing to various pathologies, including cognitive deficits and early-onset Alzheimer's disease. This study aimed...
5.
Mahmood S, Parwez H, Siddique Y, Amir M, Javed S
Mutat Res Genet Toxicol Environ Mutagen . 2024 Aug; 898:503789. PMID: 39147442
The prolonged exposure of agricultural soils to heavy metals from wastewater, particularly in areas near industrial facilities, poses a significant threat to the well-being of living organisms. The World Health...
6.
Waseem S, Masood I, Siddiqui A, Amir M, Hussain S, Husaini S
Cureus . 2024 Apr; 16(3):e56212. PMID: 38618443
Background Inflammatory markers are elevated in chronic obstructive pulmonary disease (COPD) and can be quantified to detect severity, prognosis, mortality risk, and response to treatment. However, the estimation costs are...
7.
Kamboj P, Anjali , Imtiyaz K, Rizvi M, Nath V, Kumar V, et al.
Sci Rep . 2024 Apr; 14(1):8457. PMID: 38605072
A new series of imidazothiazole derivatives bearing thiazolidinone moiety (4a-g and 5a-d) were designed, synthesized and evaluated for potential epidermal growth factor receptor (EGFR) kinase inhibition, anticancer and anti-inflammatory activity,...
8.
Kazmi M, Amir M, Iqbal M, Rashid M, Husain A
Chem Biodivers . 2023 Dec; 21(2):e202301662. PMID: 38086017
In order to determine whether thiazolobenzamide molecules connected to naphthalene could inhibit the growth of three different tumor cell lines, MCF7 (breast carcinoma), A549 (pulmonary carcinoma), and DU145 (prostatic adenocarcinoma)...
9.
Amir M, Qureshi M, Khan A, Nayeem S, Malik W, Javed S
Spectrochim Acta A Mol Biomol Spectrosc . 2023 Dec; 308:123678. PMID: 38039637
In recent times, there has been a surge in the discovery of drugs that directly interact with DNA, influencing gene expression. As a result, understanding how biomolecules interact with DNA...
10.
Amir M, Latha S, Sharma R, Kumar A
Curr Drug Saf . 2023 Nov; 19(3):402-406. PMID: 38031796
Background: COVID-19 vaccines have played a crucial role in reducing the burden of the global pandemic. However, recent case reports have indicated the association of the COVID- 19 vaccines with...