Taj Mohammad
Overview
Explore the profile of Taj Mohammad including associated specialties, affiliations and a list of published articles.
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Articles
106
Citations
1944
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0
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Recent Articles
1.
Hussain A, Mohammad T, Khan S, Alajmi M, Yadav D, Hassan M
OMICS
. 2025 Mar;
PMID: 40059764
Huntington's disease (HD) is characterized by progressive motor dysfunction and cognitive decline. Early diagnosis and new therapeutic targets are essential for effective interventions. We performed integrative analyses of mRNA profiles...
2.
Ahmed S, Saeed M, Choudhury A, Mohammad T, Hussain A, Alajmi M, et al.
OMICS
. 2025 Feb;
29(3):105-115.
PMID: 39969899
Interleukin-2-inducible T-cell kinase (ITK) is a critical tyrosine kinase enzyme that is involved in the activation and differentiation of T cells. ITK is mainly found in T cells, which plays...
3.
Sulaimani M, Ahmed S, Anjum F, Mohammad T, Shamsi A, Dohare R, et al.
PLoS One
. 2025 Jan;
20(1):e0311954.
PMID: 39854344
Mitogen-activated protein kinase 1 (MAPK1) is a serine/threonine kinase that plays a crucial role in the MAP kinase signaling transduction pathway. This pathway plays a crucial role in various cellular...
4.
Taufeeq M, Choudhury A, Hussain A, Alajmi M, Mohammad T, Shamsi A, et al.
J Alzheimers Dis
. 2025 Jan;
103(4):1226-1244.
PMID: 39814427
Background: Extracellular signal-regulated kinase 1 (ERK1) belongs to mitogen-activated protein kinases, which are essential for memory formation, cognitive function, and synaptic plasticity. During Alzheimer's disease (AD), ERK1 phosphorylates tau at...
5.
Hussain A, Mohammad T, Gulzar M, Alajmi M, Yadav D, Hassan M
OMICS
. 2025 Jan;
29(2):60-71.
PMID: 39792454
There is a growing interest in harnessing natural compounds and bioactive phytochemicals to accelerate drug discovery and development, including in the treatment of human cancers. Receptor tyrosine kinases (RTKs) are...
6.
Atre R, Obukhov A, Majmudar C, Nair K, White F, Sharma R, et al.
Eur J Pharmacol
. 2024 Dec;
987:177160.
PMID: 39631651
Dorzolamide (DZD), a Carbonic anhydrase (CA) inhibitor clinically used to lower intraocular pressure, exhibits anti-inflammatory effects owing to the drug's ability to inhibit the TIR domain-containing adaptor protein (TIRAP)-mediated signalling...
7.
Saeed M, Ahmed S, Choudhury A, Hussain A, Alajmi M, Mohammad T, et al.
Arch Microbiol
. 2024 Nov;
206(12):472.
PMID: 39565390
RfaH is a crucial protein involved in anti-termination of transcription, which is necessary for spreading virulence in certain types of bacteria, such as Klebsiella pneumoniae and Escherichia coli. RfaH works...
8.
Aazad A, Choudhury A, Hussain A, Alajmi M, Mohammad T, Prabha S, et al.
J Alzheimers Dis
. 2024 Nov;
102(3):703-719.
PMID: 39523500
Background: Alzheimer's disease (AD) is characterized by neurodegeneration linked to amyloid-β (Aβ) plaques and tau protein tangles. Protein kinase C alpha (PKCα) plays a crucial role in modulating amyloid-β protein...
9.
Habib I, Sulaimani M, Jairajpuri D, Hussain A, Mohammad T, Alajmi M, et al.
Front Mol Biosci
. 2024 Oct;
11:1492847.
PMID: 39473823
Platelet-derived growth factor receptor beta (PDGFRβ) belongs to the receptor tyrosine kinase (RTK) protein family and is implicated in several disorders such as hematopoietic, glial, and soft-tissue cancer, non-cancerous disorders,...
10.
Elasbali A, Anjum F, Al-Ghabban B, Shafie A, Mohammad T, Hassan M
OMICS
. 2024 Oct;
28(11):573-583.
PMID: 39388097
Protein kinases are key targets for cancer therapies, with the c-Met receptor tyrosine kinase (MET) and its ligand, hepatocyte growth factor, playing a role in various cancers, including non-small cell...