Mohan R Dasu
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Explore the profile of Mohan R Dasu including associated specialties, affiliations and a list of published articles.
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24
Citations
1399
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Recent Articles
1.
Yang H, Fierro F, So M, Yoon D, Nguyen A, Gallegos A, et al.
Stem Cells Transl Med
. 2020 Jul;
9(11):1353-1364.
PMID: 32720751
Diabetic foot ulcers are a major health care concern with limited effective therapies. Mesenchymal stem cell (MSC)-based therapies are promising treatment options due to their beneficial effects of immunomodulation, angiogenesis,...
2.
Dasu M, Ramirez S, La T, Gorouhi F, Nguyen C, Lin B, et al.
Stem Cells Transl Med
. 2014 Apr;
3(6):745-59.
PMID: 24760207
Previous studies demonstrate that skin wounds generate epinephrine (EPI) that can activate local adrenergic receptors (ARs), impairing healing. Bacterially derived activators of Toll-like receptors (TLRs) within the wound initiate inflammatory...
3.
Dasu M, Martin S
World J Diabetes
. 2014 Apr;
5(2):219-23.
PMID: 24748934
Aim: To examine the contribution of toll-like receptors (TLRs) expression and activation to the prolonged inflammation often seen in human diabetic wounds. Methods: Debridement wound tissue was collected from diabetic...
4.
Dasu M, Jialal I
J Diabetes Complications
. 2013 Jun;
27(5):417-21.
PMID: 23773694
Toll-like receptor-4 (TLR4) is a sentinel pathogen recognition receptor with a pivotal role in inflammation, tissue injury, diabetes and its complications. The aim of the study was to examine the...
5.
Chahal D, Sivamani R, Isseroff R, Dasu M
Phytother Res
. 2012 Nov;
27(10):1423-38.
PMID: 23147906
Plant-based extracts present a large source of natural immune modulators, many of which have been used in traditional medicine for centuries. Recent research efforts have identified plant extracts as potential...
6.
Dasu M, Isseroff R
J Invest Dermatol
. 2012 Jul;
132(8):1955-8.
PMID: 22797299
Toll-like receptors (TLRs) are considered to be the first responders in the defense against invading pathogens. TLR engagement by ligands triggers inflammatory responses in injury and trauma, and thus can...
7.
Dasu M, Ramirez S, Isseroff R
Clin Sci (Lond)
. 2011 Nov;
122(5):203-14.
PMID: 22070434
Diabetes is a mutifactorial metabolic disorder that leads to a number of complications. Diabetes is estimated to affect 36 million people in the U.S.A., and the prevalence of diagnosed and...
8.
Dasu M, Jialal I
Am J Physiol Endocrinol Metab
. 2010 Oct;
300(1):E145-54.
PMID: 20959532
Type 2 diabetes (T2DM) is characterized by hyperglycemia, dyslipidemia, and increased inflammation. Previously, we showed that high glucose (HG) induces Toll-like receptor (TLR) expression, activity, and inflammation via NF-κB followed...
9.
Dasu M, Thangappan R, Bourgette A, DiPietro L, Isseroff R, Jialal I
Lab Invest
. 2010 Aug;
90(11):1628-36.
PMID: 20733560
Toll-like receptor-2 (TLR2) is a pivotal pathogen recognition receptor that has a key role in inflammation, diabetes, and injury. Hyperglycemia, inflammation, and oxidative stress induce TLR2-myeloid differentiation factor-88 (MyD88) expression...
10.
Valleggi S, Devaraj S, Dasu M, Jialal I
Clin Chem
. 2010 May;
56(8):1345-8.
PMID: 20472823
Background: C-reactive protein (CRP) inhibits the activity of the endothelial isoform of nitric oxide synthase (eNOS) via uncoupling of the enzyme both in vitro and in vivo. eNOS activity appears...