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Mohammed Z H Farooqui

Explore the profile of Mohammed Z H Farooqui including associated specialties, affiliations and a list of published articles. Areas
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Articles 21
Citations 2085
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Recent Articles
1.
Baskar S, Peng H, Gaglione E, Carstens E, Lindorfer M, Ahn I, et al.
Blood . 2025 Jan; PMID: 39774793
Monoclonal antibodies (mAbs) improve survival of patients with mature B-cell malignancies. Fcγ-receptor dependent effector mechanisms kill tumor cells but can promote antigen loss through trogocytosis, contributing to treatment failures. Cell-bound...
2.
Huntington S, Cheng W, Sarpong E, Leng S, Farooqui M, Agu U, et al.
Leuk Lymphoma . 2024 May; 65(7):932-942. PMID: 38696747
With increasing focus on novel targeted therapies for chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL), this longitudinal claims-based study evaluated real-world CLL/SLL treatment sequences, particularly sequential targeted therapy. Among patients with...
3.
Woyach J, Stephens D, Flinn I, Bhat S, Savage R, Chai F, et al.
Cancer Discov . 2023 Nov; 14(1):66-75. PMID: 37930156
Significance: This first-in-human phase I study demonstrates the safety and preliminary efficacy of nemtabrutinib in patients with relapsed/refractory B-cell malignancies. These data support further exploration of nemtabrutinib in larger clinical...
4.
Andre T, Shiu K, Kim T, Jensen B, Jensen L, Punt C, et al.
N Engl J Med . 2020 Dec; 383(23):2207-2218. PMID: 33264544
Background: Programmed death 1 (PD-1) blockade has clinical benefit in microsatellite-instability-high (MSI-H) or mismatch-repair-deficient (dMMR) tumors after previous therapy. The efficacy of PD-1 blockade as compared with chemotherapy as first-line...
5.
Liao J, Farooqui M, Marinello P, Hartzel J, Anderson K, Ma J, et al.
Contemp Clin Trials . 2020 Oct; 99:106179. PMID: 33086159
The phase III, randomized, active-controlled, multicenter, open-label KEYNOTE-183 study (NCT02576977) evaluating pomalidomide and low dose dexamethasone (standard-of-care [SOC]) with or without pembrolizumab in patients with refractory or relapsed and refractory...
6.
Sun C, Nierman P, Kendall E, Cheung J, Gulrajani M, Herman S, et al.
Blood . 2020 Mar; 136(1):93-105. PMID: 32202637
Inhibition of the B-cell receptor pathway, and specifically of Bruton tyrosine kinase (BTK), is a leading therapeutic strategy in B-cell malignancies, including chronic lymphocytic leukemia (CLL). Target occupancy is a...
7.
Usmani S, Schjesvold F, Oriol A, Karlin L, Cavo M, Rifkin R, et al.
Lancet Haematol . 2019 Jul; 6(9):e448-e458. PMID: 31327689
Background: Lenalidomide and dexamethasone has been a standard of care in transplant-ineligible patients with newly diagnosed multiple myeloma. The addition of a third drug to the combination is likely to...
8.
Mateos M, Orlowski R, Ocio E, Rodriguez-Otero P, Reece D, Moreau P, et al.
Br J Haematol . 2019 May; 186(5):e117-e121. PMID: 31090915
No abstract available.
9.
Ribrag V, Avigan D, Green D, Wise-Draper T, Posada J, Vij R, et al.
Br J Haematol . 2019 Apr; 186(3):e41-e44. PMID: 30937889
No abstract available.
10.
Ahn I, Farooqui M, Tian X, Valdez J, Sun C, Soto S, et al.
Blood . 2018 Feb; 131(21):2357-2366. PMID: 29483101
The safety and efficacy of ibrutinib (420 mg) in chronic lymphocytic leukemia (CLL) were evaluated in a phase 2 study; 51 patients had aberration (TP53 cohort) and 35 were enrolled...