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Mohammed E Abdel-Hamid

Explore the profile of Mohammed E Abdel-Hamid including associated specialties, affiliations and a list of published articles. Areas
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Articles 10
Citations 41
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Recent Articles
1.
Novotny L, Sharaf L, Abdel-Hamid M, Brtko J
Gen Physiol Biophys . 2018 Feb; 37(1):93-99. PMID: 29424354
Triorganotins belong to toxic components present predominantly in antifouling paints for marine vessels. Tributyltin/triphenyltin at pico- or nanomolar concentrations in sea water are known to induce an irreversible sexual abnormality...
2.
Phillips O, Udo E, Abdel-Hamid M, Varghese R
Eur J Med Chem . 2013 Jul; 66:246-57. PMID: 23811087
A series of 1H-1,2,3-triazolyl piperazino oxazolidinone analogs with optionally varied glycinyl substitutions were synthesized and their antibacterial activity assessed against a panel of susceptible and resistant Gram-positive and selected Gram-negative...
3.
Phillips O, Udo E, Abdel-Hamid M, Varghese R
Arch Pharm (Weinheim) . 2012 Aug; 345(10):790-803. PMID: 22886578
A number of 1,2,3-triazolylmethyl piperazino oxazolidinone derivatives with optionally varied substituents at the 4N-piperazine position were synthesized and their antibacterial activity evaluated against a panel of susceptible and resistant Gram-positive...
4.
Phillips O, Sharaf L, Abdel-Hamid M, Varghese R
Med Princ Pract . 2010 Dec; 20(1):51-9. PMID: 21160215
Objectives: To evaluate the stability of 12 triazolyl oxazolidinone (TOZ) derivatives in simulated gastric and intestinal fluids as well as in human plasma at 37 ± 1°C. Materials And Methods:...
5.
Phillips O, Udo E, Abdel-Hamid M, Varghese R
Eur J Med Chem . 2009 Apr; 44(8):3217-27. PMID: 19376613
A series of 5-(4-methyl-1,2,3-triazole)methyl oxazolidinones were synthesized and tested for their antibacterial activity against a panel of Gram-positive and Gram-negative clinical isolates in comparison with linezolid and vancomycin. Most of...
6.
Phillips O, Abdel-Hamid M
J Pharm Pharm Sci . 2009 Feb; 11(2):22s-31s. PMID: 19203468
Unlabelled: Triazolylmethyl oxazolidinones are novel potent antibacterial agents recently synthesized in our laboratory. Purpose: Development of a rapid and specific LC-MS method for evaluating the stability of three potentially active...
7.
Abdel-Hamid M, Phillips O
J Pharm Biomed Anal . 2003 Aug; 32(6):1167-74. PMID: 12907260
Synercid is a combination of two semisynthetic pristinamycin derivatives, quinupristin and dalfopristin in 30:70 (w/w) ratio. A rapid and specific high-performance liquid chromatography-mass spectrometry was developed for the determination of...
8.
Novotny L, Abdel-Hamid M, Hamza H, Masterova I, Grancai D
J Pharm Biomed Anal . 2003 Apr; 31(5):961-8. PMID: 12684108
Ursolic acid is a hydroxy pentacyclic triterpene, which has a chemoprotective activity in human. A reliable and reproducible liquid chromatography-mass spectrometric assay (LC-MS) was developed for the determination of ursolic...
9.
Abdel-Hamid M, Edafiogho I, Scott K
J Pharm Biomed Anal . 2002 Nov; 30(4):1001-11. PMID: 12408891
Enaminones, E139, DM5 and DM27, have been recently recognized as potential anticonvulsant compounds. The molecular masses of these enarminones were proven using ion trap Finnigan mass spectrometer. For conduction of...
10.
Abdel-Hamid M, Edafiogho I, Hamza H
J Pharm Biomed Anal . 2001 Oct; 27(1-2):225-34. PMID: 11682230
The stability of the new chemical synthetic enaminone derivative (E118) was investigated using a stability-indicating high-performance liquid chromatography (HPLC) procedure. The examined samples were analyzed using a chiral HSA column...