Mohammed Akhter Hossain
Overview
Explore the profile of Mohammed Akhter Hossain including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
123
Citations
1306
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Feng Y, Escudero Castelan N, Hossain M, Wu H, Katayama H, Smith S, et al.
BMC Biol
. 2025 Feb;
23(1):59.
PMID: 40001176
Background: Relaxins are a family of peptides that regulate reproductive physiology in vertebrates. Evidence that this is an evolutionarily ancient role of relaxins has been provided by the discovery of...
2.
Wu H, Hartono H, Handley T, Hoare B, Rosengren K, Chalmers D, et al.
J Med Chem
. 2024 Nov;
67(23):20966-20979.
PMID: 39568362
Insulin-like peptide 5 (INSL5) targets the G protein-coupled receptor, relaxin family peptide receptor 4 (RXFP4), predominantly coexpressed in the colorectum. While INSL5 also binds to the related receptor RXFP3, it...
3.
Hossain M, Alom M, Kader M, Hossain M, Halim M
ACS Phys Chem Au
. 2024 Sep;
4(5):464-475.
PMID: 39346608
HIV-1 integrase (IN), a major protein in the HIV life cycle responsible for integrating viral cDNA into the host DNA, represents a promising drug target. Small peptides have emerged as...
4.
Ali M, Mahmud S, Faruque M, Hossain M, Hossain M, Kibria K
Vaccine X
. 2024 May;
18:100493.
PMID: 38812954
Background: Shigellosis is one of the significant causes of diarrhea in Bangladesh. It is a global health problem; approximately 1.3 million people die yearly from Shigellosis. The current treatment method,...
5.
Navarro-Sanchez M, Gil-Miravet I, Montero-Caballero D, Bathgate R, Hossain M, Castillo-Gomez E, et al.
Biochem Pharmacol
. 2024 May;
225:116264.
PMID: 38710334
The retrosplenial cortex (RSC) plays a central role in processing contextual fear conditioning. In addition to corticocortical and thalamocortical projections, the RSC receives subcortical inputs, including a substantial projection from...
6.
Wu H, Handley T, Hoare B, Hartono H, Scott D, Chalmers D, et al.
Biochem Pharmacol
. 2024 Apr;
224:116239.
PMID: 38679208
Human insulin-like peptide 5 (INSL5) is a gut hormone produced by colonic L-cells, and its biological functions are mediated by Relaxin Family Peptide Receptor 4 (RXFP4). Our preliminary data indicated...
7.
Wu H, Hoare B, Handley T, Hossain M, Bathgate R
Biochem Pharmacol
. 2024 Apr;
224:116238.
PMID: 38677442
INSL5 and relaxin-3 are relaxin family peptides with important roles in gut and brain function, respectively. They mediate their actions through the class A GPCRs RXFP4 and RXFP3. RXFP4 has...
8.
Wu H, Praveen P, Handley T, Chandrashekar C, Cummins S, Bathgate R, et al.
Chemistry
. 2024 Apr;
30(33):e202400933.
PMID: 38609334
A relaxin-like gonad-stimulating peptide (RGP), Aso-RGP, featuring six cysteine residues, was identified in the Crown-of-Thorns Starfish (COTS, Acanthaster cf. solaris) and initially produced through recombinant yeast expression. This method yielded...
9.
Chandrashekar C, Lin F, Nishiuchi Y, Mohammed S, White B, Arsenakis Y, et al.
J Med Chem
. 2024 Mar;
67(9):7276-7282.
PMID: 38465973
Glucagon-like peptide receptor (GLP-1R) agonists (e.g., semaglutide, liraglutide, etc.) are efficient treatment options for people with type 2 diabetes and obesity. The manufacturing method to produce semaglutide, a blockbuster GLP-1...
10.
Handley T, Praveen P, Tailhades J, Wu H, Bathgate R, Hossain M
Int J Mol Sci
. 2023 Aug;
24(16).
PMID: 37628851
Human relaxin-2 (H2 relaxin) is a peptide hormone with potent vasodilatory and anti-fibrotic effects, which is of interest for the treatment of heart failure and fibrosis. H2 relaxin binds to...