Mohammed Akaaboune
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Explore the profile of Mohammed Akaaboune including associated specialties, affiliations and a list of published articles.
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35
Citations
608
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Recent Articles
1.
Barden J, Kosloski O, Jadidian A, Akaaboune M
J Cell Sci
. 2024 Nov;
137(24).
PMID: 39575567
The muscle-specific microRNA miR-206 has recently emerged as a potential regulator of genes involved in the formation and regeneration of the neuromuscular junction (NMJ). This study investigated miR-206-3p (miR-206) expression...
2.
Malik S, Wierenga A, Gao C, Akaaboune M
Hum Mol Genet
. 2024 Mar;
33(13):1107-1119.
PMID: 38507070
The dystrophin-glycoprotein complex (DGC) plays a crucial role in maintaining the structural integrity of the plasma membrane and the neuromuscular junction. In this study, we investigated the impact of the...
3.
Valenzuela I, Chen P, Barden J, Kosloski O, Akaaboune M
Hum Mol Genet
. 2022 Feb;
31(14):2370-2385.
PMID: 35157076
α-syntrophin (α-syn) and α-dystrobrevin (α-dbn), two components of the dystrophin-glycoprotein complex, are essential for the maturation and maintenance of the neuromuscular junction (NMJ) and mice deficient in either α-syn or...
4.
Valenzuela I, Akaaboune M
Cells
. 2021 Feb;
10(2).
PMID: 33572348
The clustering and maintenance of nicotinic acetylcholine receptors (AChRs) at high density in the postsynaptic membrane is a hallmark of the mammalian neuromuscular junction (NMJ). The regulation of receptor density/turnover...
5.
Chen P, Zelada D, Belhasan D, Akaaboune M
J Biol Chem
. 2020 Jun;
295(31):10677-10688.
PMID: 32532815
The maintenance of a high density of the acetylcholine receptor (AChR) is the hallmark of the neuromuscular junction. Muscle-specific anchoring protein (αkap) encoded within the calcium/calmodulin-dependent protein kinase IIα (CAMK2A)...
6.
Valenzuela I, Akaaboune M
Mol Metab
. 2020 Apr;
36:100979.
PMID: 32283080
Objective: A sustained high fat diet in mice mimics many features of human obesity. We used male and female Non-Swiss albino mice to investigate the impact of short and long-term...
7.
Belhasan D, Akaaboune M
Neurosci Lett
. 2020 Feb;
722:134833.
PMID: 32057921
The Dystrophin Glycoprotein Complex (DGC) is a large multi-protein complex that links cytoskeleton actin to the extracellular matrix. This complex is critical in maintaining the structural integrity of muscle fibers...
8.
Lissek T, Adams M, Adelman J, Ahissar E, Akaaboune M, Akil H, et al.
Neuron
. 2017 Nov;
96(4):730-735.
PMID: 29144972
Science is ideally suited to connect people from different cultures and thereby foster mutual understanding. To promote international life science collaboration, we have launched "The Science Bridge" initiative. Our current...
9.
Herranz-Martin S, Chandran J, Lewis K, Mulcahy P, Higginbottom A, Walker C, et al.
Dis Model Mech
. 2017 May;
10(7):859-868.
PMID: 28550099
Intronic GGGGCC repeat expansions in are the most common genetic cause of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). Two major pathologies stemming from the hexanucleotide RNA expansions (HREs)...
10.
Aittaleb M, Valenzuela I, Akaaboune M
J Cell Sci
. 2017 Apr;
130(10):1752-1759.
PMID: 28364093
A bimolecular fluorescence complementation (BiFC) approach was used to study the molecular interactions between different components of the postsynaptic protein complex at the neuromuscular junction of living mice. We show...