Mohammad Rehan Ajmal
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Explore the profile of Mohammad Rehan Ajmal including associated specialties, affiliations and a list of published articles.
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34
Citations
154
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Recent Articles
11.
Almutairi F, Ajmal M, Alawy A, Khan R, Abdelhameed A
ScientificWorldJournal
. 2020 Sep;
2020:8363685.
PMID: 32908463
In the present study, we employ fluorescence spectroscopy, dynamic light scattering, and molecular docking methods. Binding of anticancer drug anastrozole with human lysozyme (HL) is studied. Binding of anastrozole to...
12.
Siddiqi M, Nusrat S, Alam P, Malik S, Chaturvedi S, Ajmal M, et al.
Int J Biol Macromol
. 2020 Apr;
157:774.
PMID: 32331792
No abstract available.
13.
Almutairi F, Ajmal M, Siddiqi M, Majid N, Ahmad Al-Alawy A, Abdelhameed A, et al.
J Biomol Struct Dyn
. 2020 Apr;
39(5):1525-1534.
PMID: 32308140
Interaction of levocabastine with human serum albumin (HSA) is investigated by applying fluorescence spectroscopy, circular dichroism spectroscopy and molecular docking methods. Levocabastine is an important drug in treatment of allergy...
14.
Ajmal M, Almutairi F, Zaidi N, Alam P, Siddiqi M, Khan M, et al.
J Biomol Struct Dyn
. 2018 Apr;
37(6):1390-1401.
PMID: 29669491
Alpha1-acid glycoprotein (AAG) is a major acute phase protein of human plasma. Binding of clofazimine to AAG is investigated using optical spectroscopy and molecular docking tools. We found significant quenching...
15.
Zaman M, Khan M, Zakariya S, Nusrat S, Meeran S, Alam P, et al.
J Cell Biochem
. 2018 Jan;
119(5):3945-3956.
PMID: 29350433
Protein misfolding and aggregation lead to amyloid generation that in turn may induce cell membrane disruption and leads to cell apoptosis. In an effort to prevent or treat amyloidogenesis, large...
16.
Nusrat S, Masroor A, Zaman M, Siddiqi M, Ajmal M, Zaidi N, et al.
Int J Biol Macromol
. 2017 Nov;
109:1132-1139.
PMID: 29157902
The current study comprises of an inclusive biophysical study, enlightening the binding of L-3, 4-dihydroxyphenylalanine (l-Dopa) with human lysozyme (HL) and hen egg white lysozyme (HEWL). Spectroscopic and molecular docking...
17.
Ishtikhar M, Ahmad E, Siddiqui Z, Ahmad S, Khan M, Zaman M, et al.
Int J Biol Macromol
. 2017 Nov;
107(Pt B):2450-2464.
PMID: 29102789
Numerous phenolic compounds have been reported in the last decade that have a good antioxidant property and interaction affinity towards mammalian serum albumins. In the present study, we have utilized...
18.
Siddiqi M, Nusrat S, Alam P, Malik S, Chaturvedi S, Ajmal M, et al.
Int J Biol Macromol
. 2017 Oct;
107(Pt B):1414-1421.
PMID: 28987797
We have studied the binding of busulfan (BN) to human serum albumin (HSA) at physiological pH 7.4 by using fluorescence, UV-vis and circular dichroism (CD) spectroscopic tools, as well as...
19.
Zaman M, Zakariya S, Nusrat S, Chandel T, Meeran S, Ajmal M, et al.
Int J Biol Macromol
. 2017 Jul;
105(Pt 1):556-565.
PMID: 28716747
Protein aggregation and misfolding have been allied with numerous human disorders and thus inhibition of such occurrence has been center for intense research efforts against these diseases. Here, we investigated...
20.
Siddiqi M, Alam P, Chaturvedi S, Nusrat S, Ajmal M, Abdelhameed A, et al.
Int J Biol Macromol
. 2017 Jul;
105(Pt 1):292-299.
PMID: 28693993
The fate of drug administered to a living organism depends on drug's pharmacokinetics as well as pharmacological behavior. Serum albumins (proteins in blood plasma of human) act as a carrier...