Mitsuteru Ito
Overview
Explore the profile of Mitsuteru Ito including associated specialties, affiliations and a list of published articles.
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Articles
18
Citations
1284
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Recent Articles
1.
Loo T, Ye X, Chai R, Ito M, Bonne G, Ferguson-Smith A, et al.
Elife
. 2019 Nov;
8.
PMID: 31686651
Here we show that a major muscle specific isoform of the murine LINC complex protein SUN1 is required for efficient muscle regeneration. The nucleoplasmic domain of the isoform specifically binds...
2.
Montalban-Loro R, Lozano-Urena A, Ito M, Krueger C, Reik W, Ferguson-Smith A, et al.
Nat Commun
. 2019 Apr;
10(1):1726.
PMID: 30979904
Ten-eleven-translocation (TET) proteins catalyze DNA hydroxylation, playing an important role in demethylation of DNA in mammals. Remarkably, although hydroxymethylation levels are high in the mouse brain, the potential role of...
3.
Lorgen-Ritchie M, Murray A, Ferguson-Smith A, Richards M, Horgan G, Phillips L, et al.
PLoS One
. 2019 Apr;
14(4):e0215422.
PMID: 30969998
[This corrects the article DOI: 10.1371/journal.pone.0211799.].
4.
Lorgen-Ritchie M, Murray A, Ferguson-Smith A, Richards M, Horgan G, Phillips L, et al.
PLoS One
. 2019 Feb;
14(2):e0211799.
PMID: 30707743
Genomic imprinting is important for normal brain development and aberrant imprinting has been associated with impaired cognition. We studied the imprinting status in selected imprints (H19, IGF2, SNRPN, PEG3, MEST1,...
5.
Santangelo A, Ito M, Shiba Y, Clarke H, Schut E, Cockcroft G, et al.
Neuropsychopharmacology
. 2016 Mar;
41(9):2366-76.
PMID: 26997299
Genetic polymorphisms in the repeat upstream region of the serotonin transporter gene (SLC6A4) are associated with individual differences in stress reactivity, vulnerability to affective disorders, and response to pharmacotherapy. However,...
6.
Butcher L, Ito M, Brimpari M, Morris T, Soares F, Ahrlund-Richter L, et al.
Nat Commun
. 2016 Jan;
7:10458.
PMID: 26822956
Non-CG methylation is an unexplored epigenetic hallmark of pluripotent stem cells. Here we report that a reduction in non-CG methylation is associated with impaired differentiation capacity into endodermal lineages. Genome-wide...
7.
Ito M, Sferruzzi-Perri A, Edwards C, Adalsteinsson B, Allen S, Loo T, et al.
Development
. 2015 Jul;
142(14):2425-30.
PMID: 26138477
The paternally expressed imprinted retrotransposon-like 1 (Rtl1) is a retrotransposon-derived gene that has evolved a function in eutherian placentation. Seven miRNAs, including miR-127, are processed from a maternally expressed antisense...
8.
Radford E, Ito M, Shi H, Corish J, Yamazawa K, Isganaitis E, et al.
Science
. 2014 Jul;
345(6198):1255903.
PMID: 25011554
Adverse prenatal environments can promote metabolic disease in offspring and subsequent generations. Animal models and epidemiological data implicate epigenetic inheritance, but the mechanisms remain unknown. In an intergenerational developmental programming...
9.
Aziz A, Baxter E, Edwards C, Cheong C, Ito M, Bench A, et al.
J Clin Invest
. 2013 Apr;
123(5):2169-82.
PMID: 23543057
Large regions of recurrent genomic loss are common in cancers; however, with a few well-characterized exceptions, how they contribute to tumor pathogenesis remains largely obscure. Here we identified primate-restricted imprinting...
10.
Lim A, Ng S, Leow S, Choo R, Ito M, Chan Y, et al.
J Med Genet
. 2012 Oct;
49(11):689-97.
PMID: 23042810
Background: Genomic imprinting is a process causing genes to be expressed according to parental origin. Imprinting acts to coordinate fetal and prenatal growth, as well as control postnatal adaptations. Studies...