Miriam C Peeters
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Explore the profile of Miriam C Peeters including associated specialties, affiliations and a list of published articles.
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8
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326
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Recent Articles
1.
Peeters M, Mos I, Lenselink E, Lucchesi M, IJzerman A, Schwartz T
FASEB J
. 2016 Jan;
30(5):1836-48.
PMID: 26823453
The adhesion G protein-coupled receptors [ADGRs/class B2 G protein-coupled receptors (GPCRs)] constitute an ancient family of GPCRs that have recently been demonstrated to play important roles in cellular and developmental...
2.
Peeters M, Fokkelman M, Boogaard B, Egerod K, van de Water B, Ijzerman A, et al.
Cell Signal
. 2015 Sep;
27(12):2579-88.
PMID: 26321231
Adhesion G protein-coupled receptors (ADGRs) are believed to be activated by auto-proteolytic cleavage of their very large extracellular N-terminal domains normally acting as a negative regulator of the intrinsically constitutively...
3.
Hamann J, Aust G, Arac D, Engel F, Formstone C, Fredriksson R, et al.
Pharmacol Rev
. 2015 Feb;
67(2):338-67.
PMID: 25713288
The Adhesion family forms a large branch of the pharmacologically important superfamily of G protein-coupled receptors (GPCRs). As Adhesion GPCRs increasingly receive attention from a wide spectrum of biomedical fields,...
4.
Liebscher I, Ackley B, Arac D, Ariestanti D, Aust G, Bae B, et al.
Ann N Y Acad Sci
. 2014 Nov;
1333:43-64.
PMID: 25424900
The class of adhesion G protein-coupled receptors (aGPCRs), with 33 human homologs, is the second largest family of GPCRs. In addition to a seven-transmembrane α-helix-a structural feature of all GPCRs-the...
5.
Peeters M, Li Q, Elands R, van Westen G, Lenselink E, Muller C, et al.
Biochem Pharmacol
. 2014 Sep;
92(2):348-57.
PMID: 25179146
G protein-coupled receptors (GPCRs) are a major drug target and can be activated by a range of stimuli, from photons to proteins. Most, if not all, GPCRs also display a...
6.
Liu R, Groenewoud N, Peeters M, Lenselink E, Ijzerman A
Purinergic Signal
. 2014 Jan;
10(3):441-53.
PMID: 24464644
The expression of human G protein-coupled receptors (GPCRs) in Saccharomyces cerevisiae containing chimeric yeast/mammalian Gα subunits provides a useful tool for the study of GPCR activation. In this study, we...
7.
Peeters M, Li Q, van Westen G, Ijzerman A
Purinergic Signal
. 2011 Aug;
8(1):23-38.
PMID: 21818573
G protein-coupled receptors (GPCRs) are a major drug target and can be activated by a range of stimuli, from photons to proteins. Despite the progress made in the last decade...
8.
Peeters M, van Westen G, Guo D, Wisse L, Muller C, Beukers M, et al.
FASEB J
. 2010 Oct;
25(2):632-43.
PMID: 21030693
The highly variable extracellular loops in G protein-coupled receptors (GPCRs) have been implicated in receptor activation, the mechanism of which is poorly understood. In a random mutagenesis screen on the...