Miriam A Shelef
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Explore the profile of Miriam A Shelef including associated specialties, affiliations and a list of published articles.
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Citations
587
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Recent Articles
1.
Titi A, Krisko B, Bashar S, Adyniec R, Parker M, Murren N, et al.
Front Immunol
. 2025 Feb;
16:1553540.
PMID: 40018049
Objective: Rheumatoid factors (RFs) are a hallmark of rheumatoid arthritis but also arise in infections, including COVID-19. Moreover, infections, again including COVID-19, are associated with rheumatoid arthritis development, positioning RFs...
2.
Bashar S, Zheng Z, Mergaert A, Adyniec R, Gupta S, Amjadi M, et al.
Antibodies (Basel)
. 2024 Oct;
13(4).
PMID: 39449329
Background: Autoantibodies are commonly used as biomarkers in autoimmune diseases, but there are limitations. For example, autoantibody biomarkers have poor sensitivity or specificity in systemic lupus erythematosus and do not...
3.
Parker M, Zheng Z, Lasarev M, Larsen M, Vande Loo A, Alexandridis R, et al.
Ann Rheum Dis
. 2024 May;
83(9):1169-1180.
PMID: 38702176
Objectives: Sjögren disease (SjD) diagnosis often requires either positive anti-SSA antibodies or a labial salivary gland biopsy with a positive focus score (FS). One-third of patients with SjD lack anti-SSA...
4.
Bashar S, Holmes C, Shelef M
Front Immunol
. 2024 Mar;
15:1167362.
PMID: 38476240
Introduction: Anti-citrullinated protein antibodies (ACPAs) are a hallmark of rheumatoid arthritis, but the sources of citrullinated antigens as well as which peptidylarginine deiminases (PADs) are required for their production remain...
5.
Wang B, Li Z, Shi Y, Zhu Z, Fields L, Shelef M, et al.
Anal Chem
. 2024 Jan;
96(6):2309-2317.
PMID: 38285917
Histone citrullination is an essential epigenetic post-translational modification (PTM) that affects many important physiological and pathological processes, but effective tools to study histone citrullination are greatly limited due to several...
6.
Amjadi M, Parker M, Adyniec R, Zheng Z, Robbins A, Bashar S, et al.
J Autoimmun
. 2023 Nov;
142():103132.
PMID: 37956528
Rheumatoid factors (RFs), polyreactive antibodies canonically known to bind two conformational epitopes of IgG Fc, are a hallmark of rheumatoid arthritis but also can arise in other inflammatory conditions and...
7.
Liu C, Yalavarthi S, Tambralli A, Zeng L, Rysenga C, Alizadeh N, et al.
Sci Adv
. 2023 Oct;
9(43):eadj1019.
PMID: 37878711
While neutrophil extracellular traps (NETs) have previously been linked to some diabetes-associated complications, such as dysfunctional wound healing, their potential role in diabetic vascular dysfunction has not been studied. Diabetic...
8.
Parker M, Zheng Z, Lasarev M, Alexandridis R, Newton M, Shelef M, et al.
medRxiv
. 2023 Sep;
PMID: 37693588
Objectives: Sj□gren's disease (SjD) diagnosis requires either positive anti-SSA antibodies or a labial salivary gland biopsy with a positive focus score (FS). One-third of SjD patients lack anti-SSA antibodies (SSA-),...
9.
Circiumaru A, Afonso M, Wahamaa H, Krishnamurthy A, Hansson M, Mathsson-Alm L, et al.
Biomolecules
. 2023 May;
13(4).
PMID: 37189377
Background: Why the adaptive immune system turns against citrullinated antigens in rheumatoid arthritis (RA) and whether anti-citrullinated protein antibodies (ACPAs) contribute to pathogenesis are questions that have triggered intense research,...
10.
Deng H, Lin C, Garcia-Gerique L, Fu S, Cruz Z, Bonner E, et al.
Cancer Res
. 2022 Sep;
82(19):3561-3572.
PMID: 36069973
Significance: PAD4 regulates tumor progression by promoting neutrophil migration and can be targeted with a small molecule inhibitor to suppress tumor growth and metastasis and increase efficacy of immune checkpoint...