Miriam A Shelef
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Explore the profile of Miriam A Shelef including associated specialties, affiliations and a list of published articles.
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40
Citations
587
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Recent Articles
11.
Amjadi M, Adyniec R, Gupta S, Bashar S, Mergaert A, Braun K, et al.
J Infect Dis
. 2022 Jun;
226(11):1897-1902.
PMID: 35758987
Background: The consequences of past coronavirus disease 2019 (COVID-19) infection for personal and population health are emerging, but accurately identifying distant infection is a challenge. Anti-spike antibodies rise after both...
12.
Adi W, Biswas D, Shelef M, Yesilkoy F
Biomed Opt Express
. 2022 May;
13(4):2130-2143.
PMID: 35519285
Serological assays that can reveal immune status against COVID-19 play a critical role in informing individual and public healthcare decisions. Currently, antibody tests are performed in central clinical laboratories, limiting...
13.
Mergaert A, Warner T, Shelef M
Methods Cell Biol
. 2022 Apr;
168:125-137.
PMID: 35366979
Rheumatoid arthritis is an incurable chronic inflammatory disease for which the pathophysiology is not fully understood, and treatment options are flawed. Thus, animal models are used to dissect disease pathogenesis...
14.
Mergaert A, Denny M, Kingstad-Bakke B, Bawadekar M, Bashar S, Warner T, et al.
J Immunol Res
. 2022 Jan;
2022:5258221.
PMID: 35083342
The peptidylarginine deiminases (PADs) and the citrullinated proteins that they generate have key roles in innate immunity and rheumatoid arthritis, an inflammatory arthritis with antibodies that target citrullinated proteins. However,...
15.
Mergaert A, Zheng Z, Denny M, Amjadi M, Bashar S, Newton M, et al.
Arthritis Rheumatol
. 2022 Jan;
74(6):984-991.
PMID: 35001558
Objective: Rheumatoid arthritis (RA) patients often develop rheumatoid factors (RFs), antibodies that bind IgG Fc, and anti-modified protein antibodies (AMPAs), multireactive autoantibodies that commonly bind citrullinated, homocitrullinated, and acetylated antigens....
16.
Amjadi M, Adyniec R, Gupta S, Bashar S, Mergaert A, Braun K, et al.
medRxiv
. 2021 Nov;
PMID: 34790984
The consequences of past COVID-19 infection for personal health and long-term population immunity are only starting to be revealed. Unfortunately, detecting past infection is currently a challenge, limiting clinical and...
17.
Massarenti L, Enevold C, Damgaard D, Odum N, Garred P, Frisch M, et al.
Front Immunol
. 2021 Nov;
12:707690.
PMID: 34733271
Peptidylarginine deiminases (PADs) catalyze citrullination, a post-translational modification playing a pathogenic role in anti-citrullinated protein antibody (ACPA)-positive rheumatoid arthritis (RA). The interplay between single nucleotide polymorphisms (SNPs) in the genes...
18.
Amjadi M, OConnell S, Armbrust T, Mergaert A, Narpala S, Halfmann P, et al.
Immunohorizons
. 2021 Aug;
5(6):466-476.
PMID: 34398806
Lasting immunity will be critical for overcoming COVID-19. However, the factors associated with the development of high titers of anti-SARS-CoV-2 Abs and how long those Abs persist remain incompletely defined....
19.
Heffron A, Mcilwain S, Amjadi M, Baker D, Khullar S, Armbrust T, et al.
PLoS Biol
. 2021 Jun;
19(6):e3001265.
PMID: 34143766
The search for potential antibody-based diagnostics, vaccines, and therapeutics for pandemic severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has focused almost exclusively on the spike (S) and nucleocapsid (N) proteins....
20.
Zheng Z, Mergaert A, Ong I, Shelef M, Newton M
Bioinformatics
. 2021 Mar;
37(17):2637-2643.
PMID: 33693483
Summary: Peptide microarrays have emerged as a powerful technology in immunoproteomics as they provide a tool to measure the abundance of different antibodies in patient serum samples. The high dimensionality...