Minoru Nakayama
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Explore the profile of Minoru Nakayama including associated specialties, affiliations and a list of published articles.
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19
Citations
138
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Recent Articles
1.
Tsumaki K, Bertens C, Nakayama M, Kato S, Jonao Y, Kuribayashi A, et al.
Dis Model Mech
. 2024 Dec;
17(12).
PMID: 39629589
Variants in several genes are linked to human frontotemporal lobar degeneration (FTLD) associated with TDP43- and/or ubiquitin-positive inclusions. However, it is not yet clear whether the underlying mechanism is a...
2.
Nakayama M, Nishimura O, Nishimura Y, Kitaichi M, Kuraku S, Sone M, et al.
J Neurosci
. 2023 Apr;
43(22):3989-4004.
PMID: 37117011
The presentation of nicotinic acetylcholine receptors (nAChRs) on synaptic membranes is crucial for generating cholinergic circuits, some of which are associated with memory function and neurodegenerative disorders. Although the physiology...
3.
Saito M, Nakayama M, Fujita K, Uchida A, Yano H, Goto S, et al.
Genes Genet Syst
. 2021 Feb;
95(6):303-314.
PMID: 33583916
yata mutants of Drosophila melanogaster exhibit phenotypes including progressive brain shrinkage, developmental abnormalities and shortened lifespan, whereas in mammals, null mutations of the yata ortholog Scyl1 result in motor neuron...
4.
Furotani K, Kamimura K, Yajima T, Nakayama M, Enomoto R, Tamura T, et al.
PLoS One
. 2018 Sep;
13(9):e0204048.
PMID: 30226901
APP (amyloid precursor protein), the causative molecule of Alzheimer's disease, is synthesized in neuronal cell bodies and subsequently transported to synapses. We previously showed that the yata gene is required...
5.
Nakayama M, Nowak W, Ishikawa H, Asakawa K, Ichibe Y
EURASIP J Bioinform Syst Biol
. 2017 Feb;
2014:18.
PMID: 28194168
Background: The waveforms of the pupillary light reflex (PLR) can be analyzed in a diagnostic test that allows for differentiation between disorders affecting photoreceptors and disorders affecting retinal ganglion cells,...
6.
Nakayama M, Suzuki E, Tsunoda S, Hama C
J Neurosci
. 2016 Jan;
36(2):590-606.
PMID: 26758847
Significance Statement: The synapse has been extensively studied because it is essential for neurotransmission. By contrast, the space between the synaptic terminals, the synaptic cleft, is still an undeveloped research...
7.
Nakayama M, Matsushita F, Hama C
J Neurosci
. 2014 Oct;
34(42):13872-7.
PMID: 25319684
The synaptic cleft, a crucial space involved in neurotransmission, is filled with extracellular matrix that serves as a scaffold for synaptic differentiation. However, little is known about the proteins present...
8.
Nakayama M, Ishibashi T, Ishikawa H, Sato H, Usui T, Okuda T, et al.
BMC Genet
. 2014 Apr;
15:46.
PMID: 24739137
Background: Several lines of evidence associate misregulated genetic expression with risk factors for diabetes, Alzheimer's, and other diseases that sporadically develop in healthy adults with no background of hereditary disorders....
9.
A survey of scientific literacy to provide a foundation for designing science communication in Japan
Kawamoto S, Nakayama M, Saijo M
Public Underst Sci
. 2013 Jul;
22(6):674-90.
PMID: 23885051
There are various definitions and survey methods for scientific literacy. Taking into consideration the contemporary significance of scientific literacy, we have defined it with an emphasis on its social aspects....
10.
Maruyama S, Ohkita N, Nakayama M, Akaboshi E, Shibata T, Funakoshi E, et al.
Biol Pharm Bull
. 2012 Nov;
35(11):2017-22.
PMID: 23123473
RecQ5 is a member of the RecQ family of DNA helicases. There are 5 RecQ members in humans. Defects in 3 of them, i.e., BLM, WRN, and RTS, cause Bloom,...