Minnie Rangarajan
Overview
Explore the profile of Minnie Rangarajan including associated specialties, affiliations and a list of published articles.
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Articles
17
Citations
609
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Recent Articles
1.
Rangarajan M, Aduse-Opoku J, Hashim A, McPhail G, Luklinska Z, Haurat M, et al.
J Bacteriol
. 2017 Mar;
199(11).
PMID: 28320881
produces outer membrane vesicles (OMVs) rich in virulence factors, including cysteine proteases and A-LPS, one of the two lipopolysaccharides (LPSs) produced by this organism. Previous studies had suggested that A-LPS...
2.
Paramonov N, Aduse-Opoku J, Hashim A, Rangarajan M, Curtis M
J Bacteriol
. 2015 Mar;
197(10):1735-46.
PMID: 25733619
Unlabelled: Porphyromonas gingivalis synthesizes two lipopolysaccharides (LPSs), O-LPS and A-LPS. The structure of the core oligosaccharide (OS) of O-LPS and the attachment site of the O-polysaccharide (O-PS) repeating unit [...
3.
Rangarajan M, Aduse-Opoku J, Hashim A, Paramonov N, Curtis M
J Bacteriol
. 2013 Sep;
195(23):5297-307.
PMID: 24056103
Mannose is an important sugar in the biology of the Gram-negative bacterium Porphyromonas gingivalis. It is a major component of the oligosaccharides attached to the Arg-gingipain cysteine proteases, the repeating...
4.
Waite R, Rose R, Rangarajan M, Aduse-Opoku J, Hashim A, Curtis M
J Bacteriol
. 2012 Jun;
194(17):4521-36.
PMID: 22730125
Type I signal peptidases (SPases) cleave signal peptides from proteins during translocation across biological membranes and hence play a vital role in cellular physiology. SPase activity is also of fundamental...
5.
Curtis M, Percival R, Devine D, Darveau R, Coats S, Rangarajan M, et al.
Infect Immun
. 2011 Jan;
79(3):1187-93.
PMID: 21220483
Lipid A structure is a critical determinant of the interaction between pathogens and the innate immune system. Previously, we demonstrated the presence of non- and monophosphorylated tetra-acylated lipid A structures...
6.
Haurat M, Aduse-Opoku J, Rangarajan M, Dorobantu L, Gray M, Curtis M, et al.
J Biol Chem
. 2010 Nov;
286(2):1269-76.
PMID: 21056982
In contrast to the well established multiple cellular roles of membrane vesicles in eukaryotic cell biology, outer membrane vesicles (OMV) produced via blebbing of prokaryotic membranes have frequently been regarded...
7.
Paramonov N, Aduse-Opoku J, Hashim A, Rangarajan M, Curtis M
J Bacteriol
. 2009 Jun;
191(16):5272-82.
PMID: 19525343
Porphyromonas gingivalis synthesizes two lipopolysaccharides (LPSs), O-LPS and A-LPS. Here, we elucidate the structure of the core oligosaccharide (OS) of O-LPS from two mutants of P. gingivalis W50, Delta PG1051...
8.
Rangarajan M, Aduse-Opoku J, Paramonov N, Hashim A, Bostanci N, Fraser O, et al.
J Bacteriol
. 2008 Feb;
190(8):2920-32.
PMID: 18263730
We previously described a cell surface anionic polysaccharide (APS) in Porphyromonas gingivalis that is required for cell integrity and serum resistance. APS is a phosphorylated branched mannan that shares a...
9.
Dommisch H, Chung W, Rohani M, Williams D, Rangarajan M, Curtis M, et al.
Infect Immun
. 2007 Jun;
75(9):4326-33.
PMID: 17591792
The oral pathogen Porphyromonas gingivalis secretes proteases such as Arg-gingipain B (RgpB) that activate protease-activated receptors (PARs). Human beta-defensins (hBDs) and the macrophage inflammatory protein 3alpha/CC chemokine ligand 20 (CCL20)...
10.
Aduse-Opoku J, Slaney J, Hashim A, Gallagher A, Gallagher R, Rangarajan M, et al.
Infect Immun
. 2005 Dec;
74(1):449-60.
PMID: 16369001
Capsular polysaccharides of gram-negative bacteria play an important role in maintaining the structural integrity of the cell in hostile environments and, because of their diversity within a given species, can...