Joseph Aduse-Opoku
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Explore the profile of Joseph Aduse-Opoku including associated specialties, affiliations and a list of published articles.
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33
Citations
947
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Recent Articles
1.
Randall D, Alsam A, Kieswich J, Joseph S, Aduse-Opoku J, Swann J, et al.
Nephrol Dial Transplant
. 2024 Nov;
PMID: 39568053
Background And Hypothesis: It is presently unclear why there is a high prevalence of periodontal disease in individuals living with chronic kidney disease (CKD). Whilst some have argued that periodontal...
2.
Costeira R, Aduse-Opoku J, Vernon J, Rodriguez-Algarra F, Joseph S, Devine D, et al.
mSystems
. 2023 Jul;
8(4):e0119322.
PMID: 37436062
Periodontal disease is a chronic inflammatory disease in which the oral pathogen plays an important role. expresses virulence determinants in response to higher hemin concentrations, but the underlying regulatory processes...
3.
Dorgan B, Liu Y, Wang S, Aduse-Opoku J, Whittaker S, Roberts M, et al.
J Mol Biol
. 2022 Nov;
434(23):167871.
PMID: 36404438
Porphyromonas gingivalis is a gram-negative oral anaerobic pathogen and is one of the key causative agents of periodontitis. P. gingivalis utilises a range of virulence factors, including the cysteine protease...
4.
Aduse-Opoku J, Joseph S, Devine D, Marsh P, Curtis M
Mol Oral Microbiol
. 2022 May;
37(3):122-132.
PMID: 35622827
The periodontal pathogen Porphyromonas gingivalis is genetically heterogeneous. However, the spontaneous generation of phenotypically different sub-strains has also been reported. McKee et al. (1988) cultured P. gingivalis W50 in a...
5.
Madej M, Nowakowska Z, Ksiazek M, Lasica A, Mizgalska D, Nowak M, et al.
mBio
. 2021 Feb;
12(1).
PMID: 33622730
Cargo proteins of the type IX secretion system (T9SS) in human pathogens from the Bacteroidetes phylum invariably possess a conserved C-terminal domain (CTD) that functions as a signal for outer...
6.
Joseph S, Aduse-Opoku J, Hashim A, Hanski E, Streich R, Knowles S, et al.
mSystems
. 2021 Feb;
6(1).
PMID: 33563782
A curated murine oral microbiome database to be used as a reference for mouse-based studies has been constructed using a combination of bacterial culture, 16S rRNA gene amplicon, and whole-genome...
7.
Rangarajan M, Aduse-Opoku J, Hashim A, McPhail G, Luklinska Z, Haurat M, et al.
J Bacteriol
. 2017 Mar;
199(11).
PMID: 28320881
produces outer membrane vesicles (OMVs) rich in virulence factors, including cysteine proteases and A-LPS, one of the two lipopolysaccharides (LPSs) produced by this organism. Previous studies had suggested that A-LPS...
8.
Stephen A, Millhouse E, Sherry L, Aduse-Opoku J, Culshaw S, Ramage G, et al.
PLoS One
. 2016 Dec;
11(12):e0169157.
PMID: 28033374
Methanethiol (methyl mercaptan) is an important contributor to oral malodour and periodontal tissue destruction. Porphyromonas gingivalis, Prevotella intermedia and Fusobacterium nucleatum are key oral microbial species that produce methanethiol via...
9.
Paramonov N, Aduse-Opoku J, Hashim A, Rangarajan M, Curtis M
J Bacteriol
. 2015 Mar;
197(10):1735-46.
PMID: 25733619
Unlabelled: Porphyromonas gingivalis synthesizes two lipopolysaccharides (LPSs), O-LPS and A-LPS. The structure of the core oligosaccharide (OS) of O-LPS and the attachment site of the O-polysaccharide (O-PS) repeating unit [...
10.
Bao K, Belibasakis G, Thurnheer T, Aduse-Opoku J, Curtis M, Bostanci N
BMC Microbiol
. 2014 Oct;
14:258.
PMID: 25270662
Background: Periodontal diseases are polymicrobial diseases that cause the inflammatory destruction of the tooth-supporting (periodontal) tissues. Their initiation is attributed to the formation of subgingival biofilms that stimulate a cascade...