Miklos Sarvari
Overview
Explore the profile of Miklos Sarvari including associated specialties, affiliations and a list of published articles.
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Articles
25
Citations
337
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Recent Articles
1.
Szentkiralyi-Toth S, Gocz B, Takacs S, Sarvari M, Farkas I, Skrapits K, et al.
J Neurosci
. 2025 Jan;
45(8).
PMID: 39746822
While hypothalamic kisspeptin (KP) neurons play well-established roles in the estrogen-dependent regulation of reproduction, little is known about extrahypothalamic KP-producing (KP) neurons of the lateral septum. As established previously, expression...
2.
Gocz B, Rumpler E, Szentkiralyi-Toth S, Skrapits K, Takacs S, Sarvari M, et al.
J Biol Chem
. 2024 Dec;
301(2):108150.
PMID: 39736395
We developed a versatile 'IHC/LCM-Seq' method for spatial transcriptomics of immunohistochemically detected neurons collected with laser-capture microdissection (LCM). IHC/LCM-Seq uses aluminon and polyvinyl sulfonic acid for inventive RNA-preserving strategies to...
3.
Farkas I, Skrapits K, Sarvari M, Gocz B, Takacs S, Rumpler E, et al.
Front Endocrinol (Lausanne)
. 2024 Feb;
15:1353151.
PMID: 38348415
Reproduction in mammals is controlled by hypothalamic gonadotropin-releasing hormone (GnRH) neurons. Recent studies from our laboratory established that the basal ganglia of the human brain contain additional large populations of...
4.
Rumpler E, Gocz B, Skrapits K, Sarvari M, Takacs S, Farkas I, et al.
J Biol Chem
. 2023 Aug;
299(9):105121.
PMID: 37536628
Single-cell transcriptomics are powerful tools to define neuronal cell types based on co-expressed gene clusters. Limited RNA input in these technologies necessarily compromises transcriptome coverage and accuracy of differential expression...
5.
Gocz B, Takacs S, Skrapits K, Rumpler E, Solymosi N, Poliska S, et al.
Front Endocrinol (Lausanne)
. 2022 Sep;
13:960769.
PMID: 36093104
Kisspeptin neurons residing in the rostral periventricular area of the third ventricle (KP) and the arcuate nucleus (KP) mediate positive and negative estrogen feedback, respectively. Here, we aim to compare...
6.
Gocz B, Rumpler E, Sarvari M, Skrapits K, Takacs S, Farkas I, et al.
Proc Natl Acad Sci U S A
. 2022 Jun;
119(27):e2113749119.
PMID: 35763574
Kisspeptin neurons in the mediobasal hypothalamus (MBH) are critical targets of ovarian estrogen feedback regulating mammalian fertility. To reveal molecular mechanisms underlying this signaling, we thoroughly characterized the estrogen-regulated transcriptome...
7.
Skrapits K, Sarvari M, Farkas I, Gocz B, Takacs S, Rumpler E, et al.
Elife
. 2021 Jun;
10.
PMID: 34128468
Human reproduction is controlled by ~2000 hypothalamic gonadotropin-releasing hormone (GnRH) neurons. Here, we report the discovery and characterization of additional ~150,000-200,000 GnRH-synthesizing cells in the human basal ganglia and basal...
8.
Balla B, Sarvari M, Kosa J, Kocsis-Deak B, Tobias B, Arvai K, et al.
J Steroid Biochem Mol Biol
. 2019 Jan;
188:185-194.
PMID: 30685384
Gonadal hormones including 17β-estradiol exert important protective functions in skeletal homeostasis. However, numerous details of ovarian hormone deficiency in the common bone marrow microenvironment have not yet been revealed and...
9.
Fekete C, Vastagh C, Denes A, Hrabovszky E, Nyiri G, Kallo I, et al.
Neuroscience
. 2018 Mar;
405:35-46.
PMID: 29522854
Microglia are instrumental for recognition and elimination of amyloid β oligomers (AβOs), but the long-term consequences of AβO-induced inflammatory changes in the brain are unclear. Here, we explored microglial responses...
10.
Sarvari M, Kallo I, Hrabovszky E, Solymosi N, Liposits Z
Endocrinology
. 2016 Nov;
158(1):69-83.
PMID: 27805868
Ovarian hormones regulate the transcriptome of the hippocampus and modulate its functions. During menopause this complex signaling declines, leading to impaired learning and memory. This study was undertaken to clarify...