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Erik Hrabovszky

Explore the profile of Erik Hrabovszky including associated specialties, affiliations and a list of published articles. Areas
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Articles 81
Citations 1301
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Recent Articles
1.
Szentkiralyi-Toth S, Gocz B, Takacs S, Sarvari M, Farkas I, Skrapits K, et al.
J Neurosci . 2025 Jan; 45(8). PMID: 39746822
While hypothalamic kisspeptin (KP) neurons play well-established roles in the estrogen-dependent regulation of reproduction, little is known about extrahypothalamic KP-producing (KP) neurons of the lateral septum. As established previously, expression...
2.
Gocz B, Rumpler E, Szentkiralyi-Toth S, Skrapits K, Takacs S, Sarvari M, et al.
J Biol Chem . 2024 Dec; 301(2):108150. PMID: 39736395
We developed a versatile 'IHC/LCM-Seq' method for spatial transcriptomics of immunohistochemically detected neurons collected with laser-capture microdissection (LCM). IHC/LCM-Seq uses aluminon and polyvinyl sulfonic acid for inventive RNA-preserving strategies to...
3.
Decoster L, Trova S, Zucca S, Bulk J, Gouveia A, Ternier G, et al.
Nat Neurosci . 2024 Aug; 27(9):1758-1773. PMID: 39095587
Hypothalamic gonadotropin-releasing hormone (GnRH) neurons regulate fertility and integrate hormonal status with environmental cues to ensure reproductive success. Here we show that GnRH neurons in the olfactory bulb (GnRH) of...
4.
Ruska Y, Csibi A, Doroghazi B, Szilvasy-Szabo A, Mohacsik P, Kornyei Z, et al.
Sci Rep . 2024 Jun; 14(1):14403. PMID: 38909126
Glucagon-like peptide-1 receptor (GLP-1R) agonists are now commonly used to treat type 2 diabetes and obesity. GLP-1R signaling in the spinal cord has been suggested to account for the mild...
5.
Hrabovszky E
Nat Rev Endocrinol . 2024 Feb; 20(5):258. PMID: 38418670
No abstract available.
6.
Farkas I, Skrapits K, Sarvari M, Gocz B, Takacs S, Rumpler E, et al.
Front Endocrinol (Lausanne) . 2024 Feb; 15:1353151. PMID: 38348415
Reproduction in mammals is controlled by hypothalamic gonadotropin-releasing hormone (GnRH) neurons. Recent studies from our laboratory established that the basal ganglia of the human brain contain additional large populations of...
7.
Ruska Y, Peterfi Z, Szilvasy-Szabo A, Kovari D, Hrabovszky E, Doroghazi B, et al.
Thyroid . 2023 Dec; 34(2):252-260. PMID: 38062754
Glucagon-like peptide 1 (GLP-1) is involved in the regulation of energy and glucose homeostasis. As GLP-1 has similar effects on the energy homeostasis as the hypophysiotropic thyrotropin-releasing hormone (TRH) neurons...
8.
Sauve F, Nampoothiri S, Clarke S, Fernandois D, Ferreira Coelho C, Dewisme J, et al.
EBioMedicine . 2023 Sep; 96:104784. PMID: 37713808
Background: We have recently demonstrated a causal link between loss of gonadotropin-releasing hormone (GnRH), the master molecule regulating reproduction, and cognitive deficits during pathological aging, including Down syndrome and Alzheimer's...
9.
Rumpler E, Gocz B, Skrapits K, Sarvari M, Takacs S, Farkas I, et al.
J Biol Chem . 2023 Aug; 299(9):105121. PMID: 37536628
Single-cell transcriptomics are powerful tools to define neuronal cell types based on co-expressed gene clusters. Limited RNA input in these technologies necessarily compromises transcriptome coverage and accuracy of differential expression...
10.
Velasco I, Franssen D, Daza-Duenas S, Skrapits K, Takacs S, Torres E, et al.
Metabolism . 2023 Apr; 144:155556. PMID: 37121307
Background: Kiss1 neurons in the hypothalamic arcuate-nucleus (ARC) play key roles in the control of GnRH pulsatility and fertility. A fraction of ARC Kiss1 neurons, termed KNDy, co-express neurokinin B...