Mikkel Rohde
Overview
Explore the profile of Mikkel Rohde including associated specialties, affiliations and a list of published articles.
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Articles
18
Citations
1638
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0
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Recent Articles
1.
Rohde M, Daugaard M, Jensen M, Helin K, Nylandsted J, Jaattela M
Genes Dev
. 2024 Aug;
38(13-14):692.
PMID: 39164094
No abstract available.
2.
Anand A, Liu B, Giacobini J, Maeda K, Rohde M, Jaattela M
Mol Cancer Ther
. 2019 Jul;
18(9):1602-1614.
PMID: 31285280
Repurposing cationic amphiphilic drugs (CAD) for cancer treatment is emerging as an attractive means to enhance the efficacy of chemotherapy. Many commonly used CADs, including several cation amphiphilic antihistamines and...
3.
Corcelle-Termeau E, Vindelov S, Hamalisto S, Mograbi B, Keldsbo A, Brasen J, et al.
Autophagy
. 2016 Apr;
12(5):833-49.
PMID: 27070082
Sphingomyelin is an essential cellular lipid that traffics between plasma membrane and intracellular organelles until directed to lysosomes for SMPD1 (sphingomyelin phosphodiesterase 1)-mediated degradation. Inactivating mutations in the SMPD1 gene...
4.
Baude A, Aaes T, Zhai B, Al-Nakouzi N, Oo H, Daugaard M, et al.
Nucleic Acids Res
. 2016 Jan;
44(5):2214-26.
PMID: 26721387
We have recently identified lens epithelium-derived growth factor (LEDGF/p75, also known as PSIP1) as a component of the homologous recombination DNA repair machinery. Through its Pro-Trp-Trp-Pro (PWWP) domain, LEDGF/p75 binds...
5.
Cianfanelli V, Fuoco C, Lorente M, Salazar M, Quondamatteo F, Gherardini P, et al.
Nat Cell Biol
. 2015 May;
17(5):706.
PMID: 25925585
No abstract available.
6.
Cianfanelli V, Fuoco C, Lorente M, Salazar M, Quondamatteo F, Gherardini P, et al.
Nat Cell Biol
. 2014 Dec;
17(1):20-30.
PMID: 25438055
Inhibition of a main regulator of cell metabolism, the protein kinase mTOR, induces autophagy and inhibits cell proliferation. However, the molecular pathways involved in the cross-talk between these two mTOR-dependent...
7.
Oka Y, Varmark H, Vitting-Seerup K, Beli P, Waage J, Hakobyan A, et al.
EMBO Rep
. 2014 Aug;
15(9):956-64.
PMID: 25092792
UBL5 is an atypical ubiquitin-like protein, whose function in metazoans remains largely unexplored. We show that UBL5 is required for sister chromatid cohesion maintenance in human cells. UBL5 primarily associates...
8.
Petersen N, Olsen O, Groth-Pedersen L, Ellegaard A, Bilgin M, Redmer S, et al.
Cancer Cell
. 2013 Sep;
24(3):379-93.
PMID: 24029234
Lysosomal membrane permeabilization and subsequent cell death may prove useful in cancer treatment, provided that cancer cell lysosomes can be specifically targeted. Here, we identify acid sphingomyelinase (ASM) inhibition as...
9.
Soe M, Rohde M, Mikkelsen J, Warthoe P
Clin Chem
. 2012 Nov;
59(2):436-9.
PMID: 23115058
Background: Nucleic acid tests that can simultaneously detect multiple targets with high sensitivity, specificity, and speed are highly desirable. To meet this need, we developed a new approach we call...
10.
Daugaard M, Baude A, Fugger K, Povlsen L, Beck H, Sorensen C, et al.
Nat Struct Mol Biol
. 2012 Jul;
19(8):803-10.
PMID: 22773103
Lens epithelium-derived growth factor p75 splice variant (LEDGF) is a chromatin-binding protein known for its antiapoptotic activity and ability to direct human immunodeficiency virus into active transcription units. Here we...