Valentina Cianfanelli
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Explore the profile of Valentina Cianfanelli including associated specialties, affiliations and a list of published articles.
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36
Citations
5582
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Recent Articles
1.
Leccese A, Ruta V, Panzeri V, Attili F, Spada C, Cianfanelli V, et al.
Cancers (Basel)
. 2025 Feb;
17(4).
PMID: 40002164
Pancreatic ductal adenocarcinoma (PDAC) is a highly lethal cancer. Late diagnosis and acquisition of chemoresistance contribute to its dismal prognosis. While surgical resection improved the clinical outcome of patients, only...
2.
Migliore L, Cianfanelli V, Zevolini F, Gesualdo M, Marzuoli L, Patrussi L, et al.
Sci Rep
. 2024 Dec;
14(1):31838.
PMID: 39738384
The scaffold protein AMBRA1, which participates in the autophagy pathway, also promotes CD4 T cell differentiation to Tregs independent of autophagy through its interactor PP2A. Here we have investigated the...
3.
Faienza F, Polverino F, Rajendraprasad G, Milletti G, Hu Z, Colella B, et al.
Cell Mol Life Sci
. 2023 Aug;
80(9):251.
PMID: 37584777
AMBRA1 is a crucial factor for nervous system development, and its function has been mainly associated with autophagy. It has been also linked to cell proliferation control, through its ability...
4.
Logli E, Marzuolo E, DAgostino M, Conti L, Lena A, Diociaiuti A, et al.
Hum Mol Genet
. 2021 Nov;
31(8):1308-1324.
PMID: 34740256
Epidermolysis bullosa simplex (EBS) with cardiomyopathy (EBS-KLHL24) is an EBS subtype caused by dominantly inherited, gain-of-function mutations in the gene encoding for the ubiquitin-ligase KLHL24, which addresses specific proteins to...
5.
Simoneschi D, Rona G, Zhou N, Jeong Y, Jiang S, Milletti G, et al.
Nature
. 2021 Apr;
592(7856):789-793.
PMID: 33854235
D-type cyclins are central regulators of the cell division cycle and are among the most frequently deregulated therapeutic targets in human cancer, but the mechanisms that regulate their turnover are...
6.
Maiani E, Milletti G, Nazio F, Holdgaard S, Bartkova J, Rizza S, et al.
Nature
. 2021 Apr;
592(7856):799-803.
PMID: 33854232
Mammalian development, adult tissue homeostasis and the avoidance of severe diseases including cancer require a properly orchestrated cell cycle, as well as error-free genome maintenance. The key cell-fate decision to...
7.
Finetti F, Cassioli C, Cianfanelli V, Zevolini F, Onnis A, Gesualdo M, et al.
Front Cell Dev Biol
. 2021 Apr;
9:634003.
PMID: 33829015
Lymphocyte homeostasis, activation and differentiation crucially rely on basal autophagy. The fine-tuning of this process depends on autophagy-related (ATG) proteins and their interaction with the trafficking machinery that orchestrates the...
8.
Klionsky D, Abdel-Aziz A, Abdelfatah S, Abdellatif M, Abdoli A, Abel S, et al.
Autophagy
. 2021 Feb;
17(1):1-382.
PMID: 33634751
In 2008, we published the first set of guidelines for standardizing research in autophagy. Since then, this topic has received increasing attention, and many scientists have entered the field. Our...
9.
Cianfanelli V, Grumati P, Nazio F
Front Cell Dev Biol
. 2020 Aug;
8:664.
PMID: 32850800
No abstract available.
10.
Cianfanelli V, Cecconi F
Mol Cell Oncol
. 2020 Mar;
7(2):1719021.
PMID: 32158930
Although centrosome abnormalities are frequent in cancer, the mechanisms responsible for their accumulation are poorly understood. Here we comment on our recent publication identifying a new type of selective autophagy,...