Miki Nakamura
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Explore the profile of Miki Nakamura including associated specialties, affiliations and a list of published articles.
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63
Citations
967
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Recent Articles
1.
Nakamura M, Ohoka N, Shibata N, Inoue T, Tsuji G, Demizu Y
Bioorg Med Chem Lett
. 2024 Feb;
102:129677.
PMID: 38408510
Stimulator of interferon genes (STING), a homodimeric membrane receptor localized in the endoplasmic reticulum, plays a pivotal role in signaling innate immune responses. Inhibitors and proteolysis-targeting chimeras (PROTACs) targeting STING...
2.
Yanase Y, Tsuji G, Nakamura M, Shibata N, Demizu Y
Int J Mol Sci
. 2022 Jun;
23(12).
PMID: 35743289
Stimulator of Interferon Genes (STING) is a type of endoplasmic reticulum (ER)-membrane receptor. STING is activated by a ligand binding, which leads to an enhancement of the immune-system response. Therefore,...
3.
Togano T, Andoh S, Komuro M, Mitsui Y, Itoi S, Hirai R, et al.
Intern Med
. 2022 Apr;
61(22):3329-3334.
PMID: 35466165
Objective Currently, treatment of relapsed or refractory multiple myeloma is challenging. Although bortezomib-thalidomide-dexamethasone-cisplatin-doxorubicin-cyclophosphamide-etoposide (VTD-PACE), a potent combination of a proteasome inhibitor, immunomodulatory drug, and conventional chemotherapeutics, is a widely used...
4.
Kamimura S, Suga T, Hoki Y, Sunayama M, Imadome K, Fujita M, et al.
Stem Cell Reports
. 2021 Sep;
16(10):2503-2519.
PMID: 34559999
We here demonstrate that microsatellite (MS) alterations are elevated in both mouse and human induced pluripotent stem cells (iPSCs), but importantly we have now identified a type of human iPSC...
5.
Tanaka M, Idei M, Sakaguchi H, Kato R, Sato D, Sawanobori K, et al.
Br J Clin Pharmacol
. 2021 Mar;
87(10):4027-4035.
PMID: 33694268
The Sakigake designation system (Sakigake) has been launched to encourage the pioneered development of innovative new medical products for the effective treatment of severe illness in Japan, which allows leveraging...
6.
Nakamura M, Mikami Y, Noda K, Murata M
Biosci Biotechnol Biochem
. 2021 Feb;
85(2):401-410.
PMID: 33604624
Pentose is involved in the browning through the Maillard reaction of food derived of plant origin. During research on the Maillard reaction between xylose (Xyl) and lysine (Lys), we detected...
7.
Tanaka M, Idei M, Sakaguchi H, Kato R, Sato D, Sawanobori K, et al.
Br J Clin Pharmacol
. 2021 Jan;
87(8):3279-3291.
PMID: 33511674
Aims: To clarify the rationales of delay or difference in the review of new drug applications among regulatory authorities for new drugs, those first approved in the world being in...
8.
Tanaka M, Idei M, Sakaguchi H, Kato R, Sato D, Sawanobori K, et al.
Clin Pharmacol Ther
. 2020 Oct;
109(5):1265-1273.
PMID: 33048367
The Pharmaceuticals and Medical Devices Agency (PMDA) has approved hundreds of new drugs in recent years. We retrospectively analyzed the new drugs approved in Japan from 2008 to 2019, and...
9.
Yamamoto K, Mawatari M, Fujiya Y, Kutsuna S, Takeshita N, Hayakawa K, et al.
Infection
. 2020 Jul;
49(1):165-170.
PMID: 32720129
A 42-year-old man diagnosed with acute myeloid leukemia complained of progressive swelling of the right side of his face with pain 11 days after the third cycle of consolidation therapy...
10.
Tanimura A, Hirai R, Nakamura M, Takeshita M, Togano T, Sekine R, et al.
Gan To Kagaku Ryoho
. 2020 May;
47(5):789-796.
PMID: 32408321
Autologous stem cell transplantation(ASCT)for newly-diagnosed multiple myeloma(NDMM)has underwent recent improvements in combination with novel agents-containing induction and post-ASCT therapy. Since the approval of bortezomib for NDMM in Japan, we conducted...