Mikhail Shchepetov
Overview
Explore the profile of Mikhail Shchepetov including associated specialties, affiliations and a list of published articles.
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10
Citations
347
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Recent Articles
1.
Adams W, Bhowmick R, Bou Ghanem E, Wade K, Shchepetov M, Weiser J, et al.
J Immunol
. 2019 Nov;
204(1):101-111.
PMID: 31776202
is a major cause of pneumonia, wherein infection of respiratory mucosa drives a robust influx of neutrophils. We have previously shown that infection of the respiratory epithelium induces the production...
2.
Son M, Shchepetov M, Adrian P, Madhi S, de Gouveia L, von Gottberg A, et al.
mBio
. 2011 Sep;
2(5).
PMID: 21896678
Unlabelled: All fully sequenced strains of Streptococcus pneumoniae possess a version of the blp locus, which is responsible for bacteriocin production and immunity. Activation of the blp locus is stimulated...
3.
Nakamura S, Shchepetov M, Dalia A, Clark S, Murphy T, Sethi S, et al.
PLoS Pathog
. 2011 Jan;
7(1):e1001247.
PMID: 21253576
Non-typeable Haemophilus influenzae (NTHi), a common commensal of the human pharynx, is also an opportunistic pathogen if it becomes established in the lower respiratory tract (LRT). In comparison to colonizing...
4.
Matthias K, Roche A, Standish A, Shchepetov M, Weiser J
J Immunol
. 2008 Apr;
180(9):6246-54.
PMID: 18424747
Delivery of Ag to inductive sites, such as nasal-associated lymphoid tissue (NALT) or GALT, is thought to promote mucosal immunity. Host and microbial factors that contribute to this process were...
5.
Lysenko E, Clarke T, Shchepetov M, Ratner A, Roper D, Dowson C, et al.
PLoS Pathog
. 2007 Aug;
3(8):e118.
PMID: 17722978
Airway infection by the Gram-positive pathogen Streptococcus pneumoniae (Sp) leads to recruitment of neutrophils but limited bacterial killing by these cells. Co-colonization by Sp and a Gram-negative species, Haemophilus influenzae...
6.
Gould C, Sniegowski P, Shchepetov M, Metlay J, Weiser J
Antimicrob Agents Chemother
. 2007 Aug;
51(9):3225-9.
PMID: 17664329
The occurrence of mutator phenotypes among laboratory-generated and clinical levofloxacin-resistant strains of Streptococcus pneumoniae was determined using fluctuation analysis. The in vitro selection for levofloxacin-resistant mutants of strain D39, each...
7.
Beisswenger C, Coyne C, Shchepetov M, Weiser J
J Biol Chem
. 2007 Jul;
282(39):28700-28708.
PMID: 17650505
Streptococcus pneumoniae and Haemophilus influenzae are human pathogens that often asymptomatically colonize the mucosal surface of the upper respiratory tract, but also occasionally cause invasive disease. The ability of these...
8.
Ratner A, Aguilar J, Shchepetov M, Lysenko E, Weiser J
Cell Microbiol
. 2007 May;
9(5):1343-51.
PMID: 17474907
During mucosal colonization, epithelial cells are concurrently exposed to numerous microbial species. Epithelial cytokine production is an early component of innate immunity and contributes to mucosal defence. We have previously...
9.
Hong R, Shchepetov M, Weiser J, Axelsen P
Antimicrob Agents Chemother
. 2002 Dec;
47(1):1-6.
PMID: 12499161
Cationic antimicrobial peptides are believed to exert their primary activities on anionic bacterial cell membranes; however, this model does not adequately account for several important structure-activity relationships. These relationships are...
10.
Pericone C, Bae D, Shchepetov M, McCool T, Weiser J
J Bacteriol
. 2002 Jul;
184(16):4392-9.
PMID: 12142409
Loss-of-function mutations in the following seven pneumococcal genes were detected and analyzed: pspA, spxB, xba, licD2, lytA, nanA, and atpC. Factors associated with these mutations included (i) frameshifts caused by...