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Mike M Myerburg

Explore the profile of Mike M Myerburg including associated specialties, affiliations and a list of published articles. Areas
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Articles 18
Citations 989
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Recent Articles
1.
French A, Rockey N, Le Sage V, Mueller Brown K, Shephard M, Frizzell S, et al.
mSphere . 2023 May; 8(4):e0003923. PMID: 37255295
Secondary infection with has contributed significantly to morbidity and mortality during multiple influenza virus pandemics and remains a common threat today. During a concurrent infection, both pathogens can influence the...
2.
French A, Rockey N, Le Sage V, Mueller Brown K, Shephard M, Frizzell S, et al.
bioRxiv . 2023 Mar; PMID: 36865236
Importance: The impact of microbial communities on transmission fitness and environmental persistence is under-studied. Environmental stability of microbes is crucial to identifying transmission risks and mitigation strategies, such as removal...
3.
Corcoran T, Huber A, Hill S, Locke L, Weber L, Muthukrishnan A, et al.
Chest . 2021 May; 160(5):1604-1613. PMID: 34029561
Background: Although mucus plugging is a well-reported feature of asthma, whether asthma and type 2 inflammation affect mucociliary clearance (MCC) is unknown. Research Question: Does type 2 inflammation influence mucus...
4.
Lennox A, Coburn S, Leech J, Heidrich E, Kleyman T, Wenzel S, et al.
Sci Rep . 2018 Feb; 8(1):2109. PMID: 29391451
Allergic airway disease is known to cause significant morbidity due to impaired mucociliary clearance, however the mechanism that leads to the mucus dysfunction is not entirely understood. Interleukin 13 (IL-13),...
5.
Nturibi E, Bhagwat A, Coburn S, Myerburg M, Lakdawala S
J Virol . 2017 Jul; 91(19). PMID: 28724771
Influenza A virus (IAV) consists of eight viral RNA (vRNA) segments that are replicated in the host cell nucleus and transported to the plasma membrane for packaging into progeny virions....
6.
Lennox A, Myerburg M
Am J Respir Crit Care Med . 2017 Jun; 196(6):671-672. PMID: 28609635
No abstract available.
7.
Chen K, Campfield B, Wenzel S, McAleer J, Kreindler J, Kurland G, et al.
JCI Insight . 2016 Aug; 1(11). PMID: 27517095
Significant morbidity in cystic fibrosis (CF) results from chronic lung inflammation, most commonly due to infection. Recent data suggest that IL-17 contributes to pathological inflammation in the setting of abnormal...
8.
Heidrich E, Carattino M, Hughey R, Pilewski J, Kleyman T, Myerburg M
J Biol Chem . 2015 Mar; 290(18):11569-77. PMID: 25767115
Epithelial Na(+) channel (ENaC) function is regulated by the intracellular Na(+) concentration ([Na(+)]i) through a process known as Na(+) feedback inhibition. Although this process is known to decrease the expression...
9.
Zhao X, Wang L, Shiva S, Tejero J, Myerburg M, Wang J, et al.
Free Radic Biol Med . 2013 May; 61:428-37. PMID: 23639566
Airway lining fluid contains relatively high concentrations of nitrite, and arterial blood levels of nitrite are higher than venous levels, suggesting the lung epithelium may represent an important source of...
10.
Chen J, Winarski K, Myerburg M, Pitt B, Sheng S
J Biol Chem . 2012 Aug; 287(42):35589-35598. PMID: 22930753
Extracellular Zn(2+) activates the epithelial Na(+) channel (ENaC) by relieving Na(+) self-inhibition. However, a biphasic Zn(2+) dose response was observed, suggesting that Zn(2+) has dual effects on the channel (i.e....