Timothy E Corcoran
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Explore the profile of Timothy E Corcoran including associated specialties, affiliations and a list of published articles.
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56
Citations
731
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Recent Articles
1.
Corcoran T, Broerman M, Kliment C, Lo C
Sci Rep
. 2024 Nov;
14(1):28832.
PMID: 39572772
The mucociliary clearance (MC) system is a vital host defense against infection in the lung. MC system function is dependent on ciliary density, structure, and function and airway surface liquid...
2.
Darquenne C, Corcoran T, Lavorini F, Sorano A, Usmani O
Expert Opin Drug Deliv
. 2024 Aug;
21(8):1175-1190.
PMID: 39136493
Introduction: The deposition of inhaled medications is the first step in the pulmonary pharmacokinetic process to produce a therapeutic response. Not only lung dose but more importantly the distribution of...
3.
Niepa T, Locke L, Corcoran T, Lee J
Front Cell Infect Microbiol
. 2024 May;
14:1416131.
PMID: 38716197
No abstract available.
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Donaldson S, Corcoran T, Pilewski J, Laube B, Mogayzel P, Ceppe A, et al.
J Cyst Fibros
. 2024 Feb;
23(3):457-460.
PMID: 38355350
Many people with CF (pwCF) desire a reduction in inhaled treatment burden after initiation of elexacaftor/tezacaftor/ivacaftor. The randomized, open-label SIMPLIFY study showed that discontinuing hypertonic saline (HS) or dornase alfa...
6.
Donaldson S, Corcoran T, Pilewski J, Mogayzel P, Laube B, Boitet E, et al.
J Cyst Fibros
. 2023 Oct;
23(1):155-160.
PMID: 37845149
Background: The cystic fibrosis transmembrane conductance regulator (CFTR) modulator elexacaftor/tezacaftor/ivacaftor (E/T/I) is highly effective clinically for those with at least one F508del-CFTR allele. The effects of E/T/I on mucociliary clearance...
7.
Corcoran T, Bertrand C, Myerburg M, Weiner D, Frizzell S, Li A, et al.
ERJ Open Res
. 2023 Jan;
8(4).
PMID: 36655223
Background: Human nasal epithelial (HNE) cells can be sampled noninvasively and cultured to provide a model of the airway epithelium that reflects cystic fibrosis (CF) pathophysiology. We hypothesised that measures...
8.
Kothari S, Kefalos S, Hages N, Corcoran T, Husain S
J Aerosol Med Pulm Drug Deliv
. 2022 Dec;
35(6):307-312.
PMID: 36516401
Intravenous liposomal amphotericin B (L-AMB) has accompanying side effects that may be diminished when administering an inhaled form. Delivery systems for inhaled or aerosolized L-AMB vary, and there has not...
9.
Weiner D, Abdel-Hamid H, Corcoran T
Pediatr Pulmonol
. 2022 Mar;
57(7):1776-1778.
PMID: 35293696
No abstract available.
10.
Hages N, Sembrat J, Weber L, Johnston D, Stetten A, Sauleda M, et al.
J Aerosol Med Pulm Drug Deliv
. 2021 Oct;
35(3):146-153.
PMID: 34647795
Inhaled drug delivery can be limited by heterogeneous dose distribution. An additive that would disperse drug over the internal surfaces of the lung after aerosol deposition could improve dosing uniformity...