Mike Collins
Overview
Explore the profile of Mike Collins including associated specialties, affiliations and a list of published articles.
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Articles
13
Citations
367
Followers
0
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Recent Articles
1.
Fiskus W, Mill C, Piel J, Collins M, Hentemann M, Cuglievan B, et al.
Blood Cancer J
. 2025 Mar;
15(1):40.
PMID: 40089460
Although treatment with standard frontline therapies, including a FLT3 inhibitor (FLT3i) reduces AML burden and achieves clinical remissions, most patients with AML with FLT3 mutation relapse due to therapy-resistant stem/progenitor...
2.
Fiskus W, Piel J, Collins M, Hentemann M, Cuglievan B, Mill C, et al.
Blood
. 2024 Mar;
143(20):2059-2072.
PMID: 38437498
BRG1 (SMARCA4) and BRM (SMARCA2) are the mutually exclusive core ATPases of the chromatin remodeling BAF (BRG1/BRM-associated factor) complexes. They enable transcription factors/cofactors to access enhancers/promoter and modulate gene expressions...
3.
Seirup M, Sengupta S, Swanson S, McIntosh B, Collins M, Chu L, et al.
Genomics
. 2022 Mar;
114(3):110330.
PMID: 35278615
Primary hepatocytes are widely used in the pharmaceutical industry to screen drug candidates for hepatotoxicity, but hepatocytes quickly dedifferentiate and lose their mature metabolic function in culture. Attempts have been...
4.
Proia T, Singh M, Woessner R, Carnevalli L, Bommakanti G, Magiera L, et al.
Clin Cancer Res
. 2020 Sep;
26(23):6335-6349.
PMID: 32943458
Purpose: Danvatirsen is a therapeutic antisense oligonucleotide (ASO) that selectively targets and has shown clinical activity in two phase I clinical studies. We interrogated the clinical mechanism of action using...
5.
Whittington R, Donat K, Weber M, Kelton D, Nielsen S, Eisenberg S, et al.
BMC Vet Res
. 2019 Jun;
15(1):198.
PMID: 31196162
Paratuberculosis, a chronic disease affecting ruminant livestock, is caused by Mycobacterium avium subsp. paratuberculosis (MAP). It has direct and indirect economic costs, impacts animal welfare and arouses public health concerns....
6.
7.
Li B, Fillmore N, Bai Y, Collins M, Thomson J, Stewart R, et al.
Genome Biol
. 2015 Jan;
15(12):553.
PMID: 25608678
De novo RNA-Seq assembly facilitates the study of transcriptomes for species without sequenced genomes, but it is challenging to select the most accurate assembly in this context. To address this...
8.
Ezell S, Mayo M, Bihani T, Tepsuporn S, Wang S, Passino M, et al.
Oncotarget
. 2014 Jun;
5(13):4990-5001.
PMID: 24970801
Diffuse large B cell lymphoma is generally treated by chemotherapy and there is an unmet medical need for novel targeted therapies or combination therapies. Using in vitro screening, we have...
9.
Laing N, McDermott B, Wen S, Yang D, Lawson D, Collins M, et al.
Mol Pharmacol
. 2013 Apr;
83(6):1247-56.
PMID: 23558446
Platelet-derived growth factor receptor α (PDGFRα) is a receptor tyrosine kinase that promotes cell survival and is expressed in both the tumor and the stromal components of human cancers. We...
10.
Collins M
J Med Philos
. 2010 Feb;
35(2):154-79.
PMID: 20185451
The dead donor rule justifies current practice in organ procurement for transplantation and states that organ donors must be dead prior to donation. The majority of organ donors are diagnosed...