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Mike Bohme

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Articles 11
Citations 86
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Recent Articles
1.
Greuel S, Hanci G, Bohme M, Miki T, Schubert F, Sittinger M, et al.
Cell Prolif . 2019 May; 52(4):e12604. PMID: 31069891
Objective: For optimized expansion of human-induced pluripotent stem cells (hiPSCs) with regards to clinical applications, we investigated the influence of the inoculum density on the expansion procedure in 3D hollow-fibre...
2.
Greuel S, Freyer N, Hanci G, Bohme M, Miki T, Werner J, et al.
J Tissue Eng Regen Med . 2019 Apr; 13(7):1203-1216. PMID: 31034735
For clinical and/or pharmaceutical use of human-induced pluripotent stem cells (hiPSCs), large cell quantities of high quality are demanded. Therefore, we combined the expansion of hiPSCs in closed, perfusion-based 3D...
3.
Klapper M, Ehmke M, Palgunow D, Bohme M, Matthaus C, Bergner G, et al.
J Lipid Res . 2011 Mar; 52(6):1281-1293. PMID: 21421847
The proportions of body fat and fat-free mass are determining factors of adiposity-associated diseases. Work in Caenorhabditis elegans has revealed evolutionarily conserved pathways of fat metabolism. Nevertheless, analysis of body...
4.
Fischer A, Grallert H, Bohme M, Gieger C, Boomgaarden I, Heid I, et al.
Genet Test Mol Biomarkers . 2009 Apr; 13(2):223-6. PMID: 19371221
Context: The H-allele of the R298H polymorphism in the prostaglandin E synthase 2 (PTGES2) gene was associated with lower risk of diabetes type 2. Aim: To explore the association between...
5.
Bohme M, Grallert H, Klapper M, Gieger C, Fischer A, Heid I, et al.
Mol Nutr Food Res . 2009 Jan; 53(6):681-5. PMID: 19156719
Studies in relatively small cohorts provide preliminary evidence that functional fatty acid binding protein 2 (FABP2) promoter haplotypes are associated with type 2 diabetes and BMI. Here, we studied the...
6.
Bohme M, Grallert H, Fischer A, Gieger C, Nitz I, Heid I, et al.
Mol Genet Metab . 2008 Oct; 95(4):229-32. PMID: 18951054
The microsomal triglyceride transfer protein (MTTP) is a key regulator in the assembly and secretion of chylomicrons and very low density lipoprotein (VLDL) in the intestine and in liver. Associations...
7.
Schroder S, Fischer A, Vock C, Bohme M, Schmelzer C, Dopner M, et al.
J Athl Train . 2008 Oct; 43(5):489-504. PMID: 18833312
Context: Elite distance runners (EDR) must optimize their nutrition to maintain their demanding training schedules. Objective: To develop a nutrition concept for EDR based on energy and macronutrient expenditures. Design:...
8.
Bohme M, Nitz I, Doring F, Klapper M
Biochim Biophys Acta . 2008 Jul; 1779(10):616-21. PMID: 18634911
Variants of the human intestinal fatty acid binding protein 2 gene (FABP2) are associated with traits of the metabolic syndrome. Relevant FABP2 promoter polymorphisms c.-80_-79insT, c.-136_-132delAGTAG, c.-168_-166delAAGinsT, c.-260G>A, c.-471G>A, and...
9.
Klapper M, Bohme M, Nitz I, Doring F
Gene . 2008 Apr; 416(1-2):48-52. PMID: 18440731
The human fatty acid binding protein (FABP2) is involved in intestinal absorption and intracellular trafficking of long-chain fatty acids. Here we investigate transcriptional regulation of FABP2 by the endodermal hepatic...
10.
Klapper M, Bohme M, Nitz I, Doring F
Hum Mutat . 2007 Oct; 29(1):142-9. PMID: 17960769
The human intestinal fatty acid binding protein 2 (FABP2) mediates fat absorption by binding and intracellular trafficking of long-chain free fatty acids. Studies with knockout mice and association analysis of...