Mikala Skydsgaard
Overview
Explore the profile of Mikala Skydsgaard including associated specialties, affiliations and a list of published articles.
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14
Citations
82
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0
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Recent Articles
1.
Lauritzen B, Bjelke M, Bjorkdahl O, Bloem E, Keane K, Kjalke M, et al.
J Thromb Haemost
. 2022 Feb;
20(6):1312-1324.
PMID: 35191180
Background: Mim8 is a novel, next-generation factor VIIIa mimetic in development for subcutaneous prophylactic treatment of patients with hemophilia A with and without inhibitors. In vitro and in vivo models...
2.
Skydsgaard M, Dincer Z, Haschek W, Helke K, Jacob B, Jacobsen B, et al.
Toxicol Pathol
. 2021 Jan;
49(1):110-228.
PMID: 33393872
The INHAND (International Harmonization of Nomenclature and Diagnostic Criteria for Lesions) Project (www.toxpath.org/inhand.asp) is a joint initiative of the Societies of Toxicologic Pathology from Europe (ESTP), Great Britain (BSTP), Japan...
3.
Hvid H, Skydsgaard M, Jensen N, Viuff B, Jensen H, Oleksiewicz M, et al.
Toxicol Pathol
. 2020 Aug;
49(4):912-927.
PMID: 32840183
Quantitative assessment of proliferation can be an important endpoint in toxicologic pathology. Traditionally, cell proliferation is quantified by labor-intensive manual counting of positive and negative cells after immunohistochemical staining for...
4.
Bolze F, Williams H, Bhuwania R, Egecioglu E, Bloem E, Paulsson J, et al.
Toxicol Appl Pharmacol
. 2020 Jul;
404:115152.
PMID: 32726590
Energy metabolism and reproduction are closely linked and reciprocally regulated. The detrimental effect of underweight on reproduction complicates the safety evaluation of anti-obesity drugs, making it challenging to distinguish pathological...
5.
Viuff B, Straarup E, Nowak J, Morgills L, Skydsgaard M, Sjogren I, et al.
Toxicol Pathol
. 2019 Oct;
48(2):379-392.
PMID: 31645215
Pigs are used as a model of human obesity, both for metabolic characterization and for evaluation of pharmacological interventions. Over a period of 7 years, acute death or clinical signs...
6.
Rojas J, Bolze F, Thorup I, Nowak J, Dalsgaard C, Skydsgaard M, et al.
Toxicol Pathol
. 2018 Oct;
46(7):777-798.
PMID: 30343647
The obese rodent serves as an indispensable tool for proof-of-concept efficacy and mode-of-action pharmacology studies. Yet the utility of this disease model as an adjunct to the conventional healthy animal...
7.
Palazzi X, Burkhardt J, Caplain H, Dellarco V, Fant P, Foster J, et al.
Toxicol Pathol
. 2016 Apr;
44(6):810-24.
PMID: 27102650
The identification of adverse health effects has a central role in the development and risk/safety assessment of chemical entities and pharmaceuticals. There is currently a need for better alignment regarding...
8.
Skydsgaard M
Toxicol Pathol
. 2015 Nov;
44(3):480-1.
PMID: 26534938
The International Harmonization of Nomenclature and Diagnostic Criteria (INHAND) is a global project establishing diagnostic criteria and nomenclature for both proliferative and nonproliferative changes in laboratory animals. Nonrodent working groups...
9.
Jeppesen G, Skydsgaard M
Toxicol Pathol
. 2014 Jun;
43(2):257-66.
PMID: 24939892
The Göttingen minipig is gaining increasing popularity as a nonrodent species in nonclinical testing. The Göttingen minipig is easy to handle; has many anatomical and physiological similarities to man; and...
10.
Brink P, Skydsgaard M, Teige J, Tverdal A, Dolvik N
Am J Vet Res
. 2010 Jan;
71(1):47-54.
PMID: 20043780
Objective: To develop a scoring system for histopathologic changes in the synovium of tarsocrural joints (TCJs) of horses with osteochondritis dissecans (OCD) and to test for association between histopathologic changes...