Mikael Lund
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Explore the profile of Mikael Lund including associated specialties, affiliations and a list of published articles.
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81
Citations
690
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Recent Articles
1.
Arbring K, Lund M, Onelov L, Lindahl T
Scand J Clin Lab Invest
. 2025 Jan;
85(1):34-40.
PMID: 39854217
Background: Direct oral anticoagulants (DOACs) can interfere with coagulation analyses, causing erroneous results such as false-positive lupus anticoagulant and false-normal antithrombin, threatening patient safety when overlooked. A test using a...
2.
Bartos L, Lund M, Vacha R
Soft Matter
. 2024 Dec;
21(2):179-185.
PMID: 39628400
The diffusion of macromolecules, nanoparticles, viruses, and bacteria is essential for targeting hosts or cellular destinations. While these entities can bind to receptors and ligands on host surfaces, the impact...
3.
Vinterbladh I, Hachfi Soussi R, Forsman J, Bouhallab S, Lund M
Int J Biol Macromol
. 2024 Nov;
286():137790.
PMID: 39603294
Coacervates of oppositely charged milk proteins are used in functional food development, mainly to encapsulate bioactives. To uncover the driving forces behind coacervates formation, we study the association of lactoferrin...
4.
Hatch H, Bergonzo C, Blanco M, Yuan G, Grudinin S, Lund M, et al.
J Chem Phys
. 2024 Sep;
161(9).
PMID: 39234967
We develop a multiscale coarse-grain model of the NIST Monoclonal Antibody Reference Material 8671 (NISTmAb) to enable systematic computational investigations of high-concentration physical instabilities such as phase separation, clustering, and...
5.
Polimeni M, Zaccarelli E, Gulotta A, Lund M, Stradner A, Schurtenberger P
APL Bioeng
. 2024 Mar;
8(1):016111.
PMID: 38425712
Developing efficient and robust computational models is essential to improve our understanding of protein solution behavior. This becomes particularly important to tackle the high-concentration regime. In this context, the main...
6.
Tesei G, Hsiao Y, Dabkowska A, Gronberg G, Yanez Arteta M, Ulkoski D, et al.
Proc Natl Acad Sci U S A
. 2024 Jan;
121(2):e2311700120.
PMID: 38175863
The ionizable-lipid component of RNA-containing nanoparticles controls the pH-dependent behavior necessary for an efficient delivery of the cargo-the so-called endosomal escape. However, it is still an empirical exercise to identify...
7.
Hervo-Hansen S, Polak J, Tomandlova M, Dzubiella J, Heyda J, Lund M
J Phys Chem B
. 2023 Dec;
127(48):10253-10265.
PMID: 38058160
Salts affect the solvation thermodynamics of molecules of all sizes; the Hofmeister series is a prime example in which different ions lead to or of aqueous proteins. Early work of...
8.
Gaspar R, Lund M, Sparr E, Linse S
QRB Discov
. 2023 Aug;
1:e2.
PMID: 37528959
α-Synuclein (α-syn) is an intrinsically disordered protein with a highly asymmetric charge distribution, whose aggregation is linked to Parkinson's disease. The effect of ionic strength was investigated at mildly acidic...
9.
Kulakova A, Augustijn D, El Bialy I, Gentiluomo L, Greco M, Hervo-Hansen S, et al.
Mol Pharm
. 2023 May;
20(6):2951-2965.
PMID: 37146162
Therapeutic proteins can be challenging to develop due to their complexity and the requirement of an acceptable formulation to ensure patient safety and efficacy. To date, there is no universal...
10.
Pasquier C, Midtgaard S, Polimeni M, Jorgensen C, Arleth L, Callisen T, et al.
J Colloid Interface Sci
. 2022 Sep;
629(Pt A):794-804.
PMID: 36099847
Interactions between biomolecules are ubiquitous in nature and crucial to many applications including vaccine development; environmentally friendly textile detergents; and food formulation. Using small angle X-ray scattering and structure-based molecular...