Miguel A Moreno-Gonzalez
Overview
Explore the profile of Miguel A Moreno-Gonzalez including associated specialties, affiliations and a list of published articles.
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10
Citations
72
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Recent Articles
1.
Moreno-Gonzalez M, Zhao Z, Caparco A, Steinmetz N
Mater Adv
. 2024 Dec;
5(11):4878-4888.
PMID: 39634576
Cowpea mosaic virus is a potent intratumoral immunotherapy agent that has shown promise in preclinical studies and canine cancer trials with tumor- and tissue-agnostic efficacy. As we move towards the...
2.
de Oliveira J, Moreno-Gonzalez M, Ma Y, Deng X, Schuphan J, Steinmetz N
Mol Pharm
. 2024 Nov;
21(12):6206-6219.
PMID: 39526560
Plant viruses are naturally occurring nanoparticles and adjuvants that interact with the mammalian immune system. This property can be harnessed in vaccines and immunotherapy. We have previously demonstrated that intratumoral...
3.
Karan S, de Oliveira J, Moreno-Gonzalez M, Steinmetz N
ACS Appl Bio Mater
. 2024 Nov;
7(11):7675-7683.
PMID: 39512153
Virus-like particles (VLPs) are naturally occurring delivery platforms with potential for mRNA vaccines that can be used as an alternative to lipid nanoparticles. Here we describe a self-amplifying mRNA vaccine...
4.
Shin M, Jung E, Moreno-Gonzalez M, Ortega-Rivera O, Steinmetz N
Bioeng Transl Med
. 2024 Jan;
9(1):e10574.
PMID: 38193118
Our lab demonstrated that intratumoral Cowpea mosaic virus (CPMV) is a potent antitumor immunotherapy when used as in situ vaccine. As we pave the way for human clinical translation, formulation...
5.
Moreno-Gonzalez M, Ortega-Rivera O, Steinmetz N
Nano Today
. 2023 Oct;
50.
PMID: 37860053
Atherosclerosis is an immune-mediated chronic inflammatory disease that leads to the development of fatty plaques in the arterial walls, ultimately increasing the risk of thrombosis, stroke, and myocardial infarction. The...
6.
Ortega-Rivera O, Shin M, Moreno-Gonzalez M, Pokorski J, Steinmetz N
Adv Ther (Weinh)
. 2022 Dec;
5(10).
PMID: 36570039
The standard therapy for cardiovascular disease (CVD) is the administration of statins to reduce plasma cholesterol levels, but this requires lifelong treatment. We developed a CVD vaccine candidate that targets...
7.
Nkanga C, Ortega-Rivera O, Shin M, Moreno-Gonzalez M, Steinmetz N
Biomacromolecules
. 2022 Mar;
23(4):1812-1825.
PMID: 35344365
Cowpea mosaic virus (CPMV) is a potent immunogenic adjuvant and epitope display platform for the development of vaccines against cancers and infectious diseases, including coronavirus disease 2019. However, the proteinaceous...
8.
Ortega-Rivera O, Shukla S, Shin M, Chen A, Beiss V, Moreno-Gonzalez M, et al.
ACS Infect Dis
. 2021 Oct;
7(11):3096-3110.
PMID: 34672530
The development of vaccines against coronaviruses has focused on the spike (S) protein, which is required for the recognition of host-cell receptors and thus elicits neutralizing antibodies. Targeting conserved epitopes...
9.
Ortega-Rivera O, Shin M, Chen A, Beiss V, Moreno-Gonzalez M, Lopez-Ramirez M, et al.
J Am Chem Soc
. 2021 Sep;
143(36):14748-14765.
PMID: 34490778
The COVID-19 pandemic highlights the need for platform technologies enabling rapid development of vaccines for emerging viral diseases. The current vaccines target the SARS-CoV-2 spike (S) protein and thus far...
10.
Ahn S, Chung H, Chen W, Moreno-Gonzalez M, Vazquez-Mena O
J Chem Phys
. 2019 Dec;
151(23):234705.
PMID: 31864279
Lead sulfide quantum dots (QDs) have been widely used for various optoelectronic devices due to their high absorption coefficient and tunable bandgap. However, the low mobility of QD films results...