Miguel A Mata
Overview
Explore the profile of Miguel A Mata including associated specialties, affiliations and a list of published articles.
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Articles
6
Citations
525
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0
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Recent Articles
1.
Ooi Y, Majzoub K, Flynn R, Mata M, Diep J, Li J, et al.
Nat Microbiol
. 2019 Aug;
4(12):2369-2382.
PMID: 31384002
Flaviviruses, including dengue virus (DENV) and Zika virus (ZIKV), cause severe human disease. Co-opting cellular factors for viral translation and viral genome replication at the endoplasmic reticulum is a shared...
2.
Kuss-Duerkop S, Wang J, Mena I, White K, Metreveli G, Sakthivel R, et al.
PLoS Pathog
. 2017 Sep;
13(9):e1006635.
PMID: 28953980
Influenza A virus usurps host signaling factors to regulate its replication. One example is mTOR, a cellular regulator of protein synthesis, growth and motility. While the role of mTORC1 in...
3.
Marceau C, Puschnik A, Majzoub K, Ooi Y, Brewer S, Fuchs G, et al.
Nature
. 2016 Jul;
535(7610):159-63.
PMID: 27383987
The Flaviviridae are a family of viruses that cause severe human diseases. For example, dengue virus (DENV) is a rapidly emerging pathogen causing an estimated 100 million symptomatic infections annually...
4.
Yarbrough M, Mata M, Sakthivel R, Fontoura B
Traffic
. 2013 Dec;
15(2):127-40.
PMID: 24289861
Trafficking of proteins and RNA into and out of the nucleus occurs through the nuclear pore complex (NPC). Because of its critical function in many cellular processes, the NPC and...
5.
Kuss S, Mata M, Zhang L, Fontoura B
Viruses
. 2013 Jul;
5(7):1824-49.
PMID: 23872491
Viruses possess many strategies to impair host cellular responses to infection. Nuclear export of host messenger RNAs (mRNA) that encode antiviral factors is critical for antiviral protein production and control...
6.
Mata M, Satterly N, Versteeg G, Frantz D, Wei S, Williams N, et al.
Nat Chem Biol
. 2011 Sep;
7(10):712-9.
PMID: 21909097
A chemical genetics approach was taken to identify inhibitors of NS1, a major influenza A virus virulence factor that inhibits host gene expression. A high-throughput screen of 200,000 synthetic compounds...