Caleb D Marceau
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Explore the profile of Caleb D Marceau including associated specialties, affiliations and a list of published articles.
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12
Citations
562
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Recent Articles
1.
Belmont L, Contreras M, Cartwright-Acar C, Marceau C, Agrawal A, Levoir L, et al.
J Virol
. 2024 Oct;
98(11):e0158224.
PMID: 39377586
Under some conditions, dengue virus (DENV) can hijack IgG antibodies to facilitate its uptake into target cells expressing Fc gamma receptors (FcgR)-a process known as antibody-dependent enhancement (ADE) of infection....
2.
Belmont L, Contreras M, Cartwright-Acar C, Marceau C, Agrawal A, Levoir L, et al.
bioRxiv
. 2024 May;
PMID: 38712102
Dengue virus (DENV) can hijack non-neutralizing IgG antibodies to facilitate its uptake into target cells expressing Fc gamma receptors (FcgR) - a process known as antibody-dependent enhancement (ADE) of infection....
3.
Baggen J, Thibaut H, Hurdiss D, Wahedi M, Marceau C, van Vliet A, et al.
mBio
. 2019 Aug;
10(4).
PMID: 31409686
Encephalomyocarditis virus (EMCV) is an animal pathogen and an important model organism, whose receptor requirements are poorly understood. Here, we employed a genome-wide haploid genetic screen to identify novel EMCV...
4.
Ooi Y, Majzoub K, Flynn R, Mata M, Diep J, Li J, et al.
Nat Microbiol
. 2019 Aug;
4(12):2369-2382.
PMID: 31384002
Flaviviruses, including dengue virus (DENV) and Zika virus (ZIKV), cause severe human disease. Co-opting cellular factors for viral translation and viral genome replication at the endoplasmic reticulum is a shared...
5.
Rinis N, Golden J, Marceau C, Carette J, Van Zandt M, Gilmore R, et al.
Cell Chem Biol
. 2018 Aug;
25(10):1231-1241.e4.
PMID: 30078634
The oligosaccharyltransferase (OST) is a multisubunit enzyme complex that N-glycosylates proteins in the secretory pathway and is considered to be constitutive and unregulated. However, small-molecule OST inhibitors such as NGI-1...
6.
Puschnik A, Marceau C, Ooi Y, Majzoub K, Rinis N, Contessa J, et al.
Cell Rep
. 2017 Dec;
21(11):3032-3039.
PMID: 29241533
The mosquito-borne flaviviruses include important human pathogens such as dengue, Zika, West Nile, and yellow fever viruses, which pose a serious threat for global health. Recent genetic screens identified endoplasmic...
7.
Lebensohn A, Dubey R, Neitzel L, Tacchelly-Benites O, Yang E, Marceau C, et al.
Elife
. 2016 Dec;
5.
PMID: 27996937
The comprehensive understanding of cellular signaling pathways remains a challenge due to multiple layers of regulation that may become evident only when the pathway is probed at different levels or...
8.
Marceau C, Puschnik A, Majzoub K, Ooi Y, Brewer S, Fuchs G, et al.
Nature
. 2016 Jul;
535(7610):159-63.
PMID: 27383987
The Flaviviridae are a family of viruses that cause severe human diseases. For example, dengue virus (DENV) is a rapidly emerging pathogen causing an estimated 100 million symptomatic infections annually...
9.
Gowen B, Chim B, Marceau C, Greene T, Burr P, Gonzalez J, et al.
Elife
. 2015 Nov;
4.
PMID: 26565589
Recognition and elimination of tumor cells by the immune system is crucial for limiting tumor growth. Natural killer (NK) cells become activated when the receptor NKG2D is engaged by ligands...
10.
Popov L, Marceau C, Starkl P, Lumb J, Shah J, Guerrera D, et al.
Proc Natl Acad Sci U S A
. 2015 Oct;
112(46):14337-42.
PMID: 26489655
Staphylococcus aureus is both a transient skin colonizer and a formidable human pathogen, ranking among the leading causes of skin and soft tissue infections as well as severe pneumonia. The...