Miguel A de Pedro
Overview
Explore the profile of Miguel A de Pedro including associated specialties, affiliations and a list of published articles.
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40
Citations
3029
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Recent Articles
1.
Loza-Correa M, Ayala J, Perelman I, Hubbard K, Kalab M, Yi Q, et al.
PLoS One
. 2019 Jan;
14(1):e0211132.
PMID: 30682094
Staphylococcus epidermidis is a bacterium frequently isolated from contaminated platelet concentrates (PCs), a blood product used to treat bleeding disorders in transfusion patients. PCs offer an accidental niche for colonization...
2.
Alvarez L, Aliashkevich A, de Pedro M, Cava F
ISME J
. 2017 Oct;
12(2):438-450.
PMID: 29028003
Bacteria face tough competition in polymicrobial communities. To persist in a specific niche, many species produce toxic extracellular effectors to interfere with the growth of nearby microbes. These effectors include...
3.
Determinants of Bacterial Morphology: From Fundamentals to Possibilities for Antimicrobial Targeting
van Teeseling M, de Pedro M, Cava F
Front Microbiol
. 2017 Jul;
8:1264.
PMID: 28740487
Bacterial morphology is extremely diverse. Specific shapes are the consequence of adaptive pressures optimizing bacterial fitness. Shape affects critical biological functions, including nutrient acquisition, motility, dispersion, stress resistance and interactions...
4.
Espaillat A, Forsmo O, El Biari K, Bjork R, Lemaitre B, Trygg J, et al.
J Am Chem Soc
. 2016 Jun;
138(29):9193-204.
PMID: 27337563
Peptidoglycan is a fundamental structure for most bacteria. It contributes to the cell morphology and provides cell wall integrity against environmental insults. While several studies have reported a significant degree...
5.
Alvarez L, Hernandez S, de Pedro M, Cava F
Methods Mol Biol
. 2016 Jun;
1440:11-27.
PMID: 27311661
High-performance liquid chromatography (HPLC) analysis has been critical for determining the structural and chemical complexity of the cell wall. However this method is very time consuming in terms of sample...
6.
Desmarais S, Tropini C, Miguel A, Cava F, Monds R, de Pedro M, et al.
J Biol Chem
. 2015 Oct;
290(52):31090-100.
PMID: 26468288
The bacterial cell wall is a network of glycan strands cross-linked by short peptides (peptidoglycan); it is responsible for the mechanical integrity of the cell and shape determination. Liquid chromatography...
7.
Rico-Perez G, Pezza A, Pucciarelli M, de Pedro M, Soncini F, Garcia-Del Portillo F
Mol Microbiol
. 2015 Oct;
99(3):546-56.
PMID: 26462856
Bacteria remodel peptidoglycan structure in response to environmental changes. Many enzymes are involved in peptidoglycan metabolism; however, little is known about their responsiveness in a defined environment or the modes...
8.
de Pedro M, Cava F
Front Microbiol
. 2015 May;
6:449.
PMID: 26005443
The peptidoglycan wall (PG) is a unique structure which confers physical strength and defined shape to bacteria. It consists of a net-like macromolecule of peptide interlinked glycan chains overlying the...
9.
Alvarez L, Espaillat A, Hermoso J, de Pedro M, Cava F
Microb Drug Resist
. 2014 May;
20(3):190-8.
PMID: 24799190
The peptidoglycan (PG) cell wall constitutes the main defense barrier of bacteria against environmental insults and acts as communication interface. The biochemistry of this macromolecule has been well characterized throughout...
10.
Hernandez S, Cava F, Pucciarelli M, Garcia-Del Portillo F, de Pedro M, Casadesus J
Environ Microbiol
. 2014 Apr;
17(4):1081-9.
PMID: 24762004
Changes in the peptidoglycan (PG) structure of Salmonella enterica are detected in the presence of a sublethal concentration of sodium deoxycholate (DOC): (i) lower proportions of Braun lipoprotein (Lpp)-bound muropeptides;...