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Michiel E Adriaens

Explore the profile of Michiel E Adriaens including associated specialties, affiliations and a list of published articles. Areas
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Articles 37
Citations 760
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Recent Articles
1.
Kemper E, Goossens G, Blaak E, Adriaens M, Meex R
J Clin Endocrinol Metab . 2025 Feb; PMID: 39918061
Objective: Fetuin B is a steatosis-responsive hepatokine that induces glucose intolerance in mice. Recently, we found that fetuin B in white adipose tissue was positively associated with peripheral insulin resistance...
2.
Erdos B, ODonovan S, Adriaens M, Gijbels A, Trouwborst I, Jardon K, et al.
Sci Rep . 2024 Apr; 14(1):8037. PMID: 38580749
Continuous glucose monitoring (CGM) is a promising, minimally invasive alternative to plasma glucose measurements for calibrating physiology-based mathematical models of insulin-regulated glucose metabolism, reducing the reliance on in-clinic measurements. However,...
3.
Gijbels A, Erdos B, Trouwborst I, Jardon K, Adriaens M, Goossens G, et al.
Cardiovasc Diabetol . 2024 Mar; 23(1):97. PMID: 38493102
Background: Tissue-specific insulin resistance (IR) predominantly in muscle (muscle IR) or liver (liver IR) has previously been linked to distinct fasting metabolite profiles, but postprandial metabolite profiles have not been...
4.
Erdos B, van Sloun B, Goossens G, ODonovan S, de Galan B, van Greevenbroek M, et al.
PLoS One . 2023 Jul; 18(7):e0285820. PMID: 37498860
Computational models of human glucose homeostasis can provide insight into the physiological processes underlying the observed inter-individual variability in glucose regulation. Modelling approaches ranging from "bottom-up" mechanistic models to "top-down"...
5.
Erdos B, Westerhuis J, Adriaens M, ODonovan S, Xie R, Singh-Povel C, et al.
PLoS Comput Biol . 2023 Jun; 19(6):e1011221. PMID: 37352364
The intricate dependency structure of biological "omics" data, particularly those originating from longitudinal intervention studies with frequently sampled repeated measurements renders the analysis of such data challenging. The high-dimensionality, inter-relatedness...
6.
Verdonschot J, Wang P, Derks K, Adriaens M, Stroeks S, Henkens M, et al.
JACC Basic Transl Sci . 2023 May; 8(4):406-418. PMID: 37138803
Dilated cardiomyopathy is a heterogeneous disease characterized by multiple genetic and environmental etiologies. The majority of patients are treated the same despite these differences. The cardiac transcriptome provides information on...
7.
Catala P, Vivensang F, van Beek D, Adriaens M, Dickman M, LaPointe V, et al.
Adv Biol (Weinh) . 2023 Apr; 7(10):e2300065. PMID: 37062753
The regenerative capacity of corneal endothelial cells (CECs) differs between species; in bigger mammals, CECs are arrested in a non-proliferative state. Damage to these cells can compromise their function causing...
8.
Stroeks S, van Beek D, Adriaens M, Verdonschot J
Circ Genom Precis Med . 2023 Jan; 16(1):e003901. PMID: 36716182
No abstract available.
9.
Trouwborst I, Gijbels A, Jardon K, Siebelink E, Hul G, Wanders L, et al.
Cell Metab . 2023 Jan; 35(1):71-83.e5. PMID: 36599304
Precision nutrition based on metabolic phenotype may increase the effectiveness of interventions. In this proof-of-concept study, we investigated the effect of modulating dietary macronutrient composition according to muscle insulin-resistant (MIR)...
10.
Sarathy C, Breuer M, Kutmon M, Adriaens M, Evelo C, Arts I
PLoS Comput Biol . 2021 Nov; 17(11):e1009522. PMID: 34748535
Genome-scale metabolic models (GEMs) are comprehensive knowledge bases of cellular metabolism and serve as mathematical tools for studying biological phenotypes and metabolic states or conditions in various organisms and cell...